Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01161-5Bacterial resistance to antibiotics is a growing health threat, but its evolution outside laboratory settings is poorly understood. Bacteria living in the human gut are now found to evolve persistent resistance after brief exposure to antibiotics, and factors that promote this evolution have been identified, highlighting the gut as a potential hotspot for this process.

Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01151-7Fresh optimism surrounds initiatives to treat existing disease.

Barcelona forward Lamine Yamal said it's amazing to have young fans looking up to him in the same way he once sought inspiration from Lionel Messi.

Who are the best players in the class? Which teams need a QB? Here's our one-stop guide to the draft.

World leaders and the Catholic faithful from around the globe will attend the funeral on Saturday. Heres how to watch it and what to expect.

Senator Richard J. Durbins departure will set off a primary for a rare open Senate seat in Illinois and open a top leadership slot. He said it was time to face reality and make way for someone new.

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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08927-xSpatially resolved transcriptomic profiling of primary tumours and metastases from patients with pancreatic cancer provides insight into the evolutionary progression to metastasis, and the variation in clonal architecture within and between individuals.

Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01087-yScans of 18 ancient papyri that were buried by the eruption of Mount Vesuvius look very promising, and there are plans to digitally unroll many more.

Cincinnati transfer Dillon Mitchell has committed to St. John's, sources told ESPN.

The Lakers were motivated by a JJ Redick tirade after their lead slipped in the third quarter, closing out a 94-85 win over the Timberwolves to even their first-round series.

America needs to figure out how to dominate the industries of the future. Call me a Waymo Democrat.

Victims and eyewitnesses described scenes of chaos and horror when militants killed 26 people in Kashmir as families, couples and friends took in a picturesque valley.

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Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01132-wNeurons involved in forming memories of a cold environment communicate with the part of the brain that regulates metabolic responses to cold stress.

Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01283-wPhoenician civilization thrived across the Mediterranean for more than 1,000 years.

Saints general manager Mickey Loomis confirmed Wednesday that Derek Carr has an issue with his shoulder and said the team is hoping for more clarity in the future.

With Steve Angeli having entered the transfer portal, Notre Dame's QB competition is down to CJ Carr and Kenny Minchey.

A single image captures the subtle changes in how the Roman Catholic Church buries a pope.

Ms. Adams, the City Council speaker, won endorsements from Letitia James, the state attorney general, and from three major unions including District Council 37.

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There was a time when social media felt personal, creative, and even a little chaotic—in a good way. We posted blurry vacation pics, overshared in our status updates, and stumbled across interesting thoughts from strangers who didn't sound like robots. But lately, things have changed. Spend five minutes scrolling through Facebook, TikTok, Instagram, YouTube, X (formerly Twitter), or even...

In a region as historically rich and naturally beautiful as The Dalles, Oregon, tourism isn’t just a matter of promotion—it’s a reflection of identity, pride, and community. At the heart of this identity stands an organization that has consistently demonstrated its commitment to the city’s growth and well-being: The Dalles Chamber of Commerce. When it comes to choosing...

Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01288-5We round up some recent stories from the Nature Briefing.

Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01284-9Bendy, twisty and collapsable origami towers could make temperature controlling panels, or, dancing robots.

No. 1 draft pick Paige Bueckers said she is "super excited" for her future with a Dallas Wings organization that has a new general manager and head coach.

Jimmer Fredette, a star at BYU who went on to become an NBA lottery pick and then played for the U.S. in 3x3 basketball at last year's Paris Olympics, announced his retirement Wednesday.

The offer, which caused President Trumps memecoin to surge in price, was his familys latest effort to profit from cryptocurrencies.

The oil tanker Palanca Rio arrives in Portland, Maine, Wednesday, April 2, 2025, after a two-day voyage from St. John, New Brunswick, Canada. (AP Photo/Robert F. Bukaty, File)2025-04-23T20:51:31Z NEW YORK (AP) A dozen states sued the Trump administration in the U.S. Court of International Trade in New York on Wednesday to stop its tariff policy, saying it is unlawful and has brought chaos to the American economy.The lawsuit said the policy put in place by President Donald Trump has been subject to his whims rather than the sound exercise of lawful authority.It challenged Trumps claim that he could arbitrarily impose tariffs based on the International Emergency Economic Powers Act. The suit asks the court to declare the tariffs to be illegal, and to block government agencies and its officers from enforcing them.A message sent to the Justice Department for comment was not immediately returned.The states listed as plaintiffs in the lawsuit were Oregon, Arizona, Colorado, Connecticut, Delaware, Illinois, Maine, Minnesota, Nevada, New Mexico, New York and Vermont. In a release, Arizona Attorney General Kris Mayes called Trumps tariff scheme insane.She said it was not only economically reckless it is illegal.The lawsuit maintained that only Congress has the power to impose tariffs and that the president can only invoke the International Emergency Economic Powers Act when an emergency presents an unusual and extraordinary threat from abroad. By claiming the authority to impose immense and ever-changing tariffs on whatever goods entering the United States he chooses, for whatever reason he finds convenient to declare an emergency, the President has upended the constitutional order and brought chaos to the American economy, the lawsuit said. Last week, California Gov. Gavin Newsom, a Democrat, sued the Trump administration in U.S. District Court in the Northern District of California over the tariff policy, saying his state could lose billions of dollars in revenue as the largest importer in the country.White House spokesperson Kush Desai responded to Newsoms lawsuit, saying the Trump administration remains committed to addressing this national emergency thats decimating Americas industries and leaving our workers behind with every tool at our disposal, from tariffs to negotiations.

Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01268-9Tecovirimat, which has been approved to treat mpox, was no better than a placebo in a large trial.

Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-09025-8Geographic and age variations in mutational processes in colorectal cancer

Former USMNT coach Bruce Arena has criticized the appointment of current head coach Mauricio Pochettino, saying that a non-American lacks the necessary understanding of the country's culture.

Lauren and Jrue Holiday were announced as the newest investors of the North Carolina Courage through their Holiday Family Trust.

The presidents threats of tariffs have brought countries like Japan, South Korea and India rushing to negotiate, but they have sown chaos with bigger trading partners like China.

Mexican artists built enormous audiences singing about drug cartels and narco culture. Cities and states are now moving against the style.

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New York Knicks guard Jalen Brunson (11) drives toward the basket to make a 2-pointer at the end of Game 2 of an NBA basketball first-round playoff series against the Detroit Pistons, Monday, April 21, 2025, in New York. (AP Photo/Angelina Katsanis)2025-04-23T22:42:22Z Jalen Brunson of the New York Knicks won the NBAs clutch player of the year award on Wednesday.Brunson got 70 of the 100 first-place votes. Denvers Nikola Jokic was second and Minnesotas Anthony Edwards was third.Brunson averaged 5.6 points on 51.5% shooting in clutch time this season, with the Knicks going 17-11 in the games he played that met the criteria for the clutch designation.Brunson was truly at his best in the final 30 seconds of those clutch games. He shot 11 for 17 64.7% in those moments, including 4 for 8 from 3-point range.___AP NBA: https://apnews.com/nba TIM REYNOLDS Reynolds is an Associated Press sports writer, based in South Florida. twitter mailto

Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01269-8Researchers pinpoint the genes responsible for the final three pea traits studied by the famed citizen scientist.

Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01173-1Quantum communication over long distances can be achieved by exploiting a property of light called coherence. The coherence-based exchange of a quantum encryption key over an optical telecommunications network demonstrates the feasibility of implementing a large-scale quantum network in existing telecommunications infrastructure.

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Patrick Mahomes is hopeful that a healthy Chiefs team can have the big-play passing game in 2025 that it lacked last season.

An Indonesian man with a student visa and an American wife thought he would soon get a green card. Now, he could get deported over a 2022 arrest.

He did the cable networks play-by-play for college basketball, football and baseball games, but his most important assignment was Sunday Night Football.

Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01167-zThe high-resolution structure of a bridge-like lipid-transfer protein that moves lipids between cellular compartments shows how these lipid superhighways operate.

Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01271-0Two studies show the extent of gunshot wounds inflicted by police and link certain police-department policies with a lower death toll.

Real Madrid, Liverpool and Manchester City are all looking to sign Bournemouth's Milos Kerkez. Transfer Talk has the latest.