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Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08853-yNew fully integrated semiconductor laser architectures are shown to be able to generate bright and background-free picosecond solitons at GHz repetition rates in the mid-infrared range.

Nature, Published online: 16 April 2025; doi:10.1038/d41586-025-00688-xTransplanting dopamine-releasing neurons into the brain is a promising regenerative therapy for Parkinsons disease. Two clinical trials show that it is safe, but more evidence is needed to prove its effectiveness.

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In this photo released by the Atomic Energy Organisation of Iran, International Atomic Energy Agency (IAEA) Director General, Rafael Mariano Grossi attends a meeting with the head of the Atomic Energy Organization of Iran Mohammad Eslami, in Tehran, Iran, Thursday, April 17, 2025. (Atomic Energy Organisation of Iran via AP)2025-04-17T11:11:54Z DUBAI, United Arab Emirates (AP) Talks between Iran and the United States over Tehrans rapidly advancing nuclear program are in a very crucial stage, the head of the United Nations nuclear watchdog said Thursday while on a visit to the Islamic Republic.The comments by Rafael Mariano Grossi of the International Atomic Energy Agency in Tehran included an acknowledgment his agency likely would be key in verifying compliance by Iran should a deal be reached. Iran and the U.S. will meet again Saturday in Rome for a new round of talks after last weekends first meeting in Oman. Grossis visit also coincided with Saudi Arabias defense minister, Prince Khalid bin Salman, visiting Tehran as the highest-ranking official from the kingdom to visit Iran since the two countries reached a Chinese-mediated dtente in 2023. Thats as Saudi Arabia tries to end its decadelong war against the Iranian-backed Houthi rebels in Yemen even as a new, intense campaign of U.S. airstrikes targets them. The stakes of the negotiations Saturday and the wider geopolitical tensions in the Mideast couldnt be higher, particularly as the Israel-Hamas war rages on in the Gaza Strip. U.S. President Donald Trump repeatedly has threatened to unleash airstrikes targeting Irans nuclear program if a deal isnt reached. Iranian officials increasingly warn that they could pursue a nuclear weapon with their stockpile of uranium enriched to near weapons-grade levels. Grossi visits during crucial Iran-US talksGrossi arrived in Iran on Wednesday night and met with Iranian Foreign Minister Abbas Araghchi, who now is in Moscow for separate talks likely over the negotiations. On Thursday, Grossi met with Mohammad Eslami, the head of the Atomic Energy Organization of Iran, then later toured a hall featuring some of Irans civilian nuclear projects. We know that we are in a very crucial, I would say, stage of this important negotiation, so I want to concentrate on the positive, Grossi told Iranian media. There is a possibility of a good outcome. Nothing is guaranteed. We need to make sure that we put all of the elements in place ... in order to get to this agreement. He added: We know we dont have much time. So this is why Im here. This is why Im in contact with the United States as well.Asked about Trumps threats to attack Iran, Grossi urged people to concentrate on our objective.Once we get to our objective, all of these things will evaporate because there will be no reason for concern, he said.For his part, Eslami said Iran expected the IAEA to maintain impartiality and act professionally, a report from the state-run IRNA news agency said. Since the nuclear deals collapse in 2018 with Trumps unilateral withdrawal of the U.S. from the accord, Iran has abandoned all limits on its program, and enriches uranium to up to 60% purity near weapons-grade levels of 90%.Surveillance cameras installed by the IAEA have been disrupted, while Iran has barred some of the Vienna-based agencys most experienced inspectors. Iranian officials also have increasingly threatened that they could pursue atomic weapons, something the West and the IAEA have been worried about for years since Tehran abandoned an organized weapons program in 2003.Despite tensions between Iran and the agency, its access has not been entirely revoked. Saudi prince becomes kingdoms highest-level visitor to Tehran in decadesPrince Khalid bin Salman, the son of King Salman and the brother of Crown Prince Mohammed bin Salman, arrived in Tehran on Thursday. Irans joint chief of staff, Gen. Mohammad Bagheri, greeted the prince on his arrival and an honor guard played for the two men. Prince Khalid, a fighter pilot, has become the first Saudi defense minister to visit Iran since the 1979 Islamic Revolution. Hes also the highest-ranking Saudi royal to visit in decades. The last was King Abdullah bin Abdulaziz, who did so as crown prince in 1997 for an Organization of Islamic Cooperation meeting held in Tehran. The state-run Saudi Press Agency, announcing the princes arrival, said his trip would include a number of meetings to discuss bilateral relations between the two countries and issues of common interest, without elaborating. The visit is significant, particularly given the decades of enmity between the two countries. Saudi Arabia has been for years trying to get a peace deal agreed to with the Houthis. A de facto ceasefire broadly has halted hostilities in the war, though the Houthis increasingly have threatened both Saudi Arabia and the United Arab Emirates amid the U.S. airstrikes. ___Vahdat reported from Tehran, Iran. Associated Press writer Stephanie Liechtenstein in Vienna contributed to this report. JON GAMBRELL Gambrell is the news director for the Gulf and Iran for The Associated Press. He has reported from each of the Gulf Cooperation Council countries, Iran and other locations across the world since joining the AP in 2006. twitter instagram mailto

Delegate of the Holy Father, Cardinal Domenico Calcagno, presides over the Chrism Mass inside St. Peter's Basilica at The Vatican, Thursday, April. 17, 2025. (AP Photo/Andrew Medichini)2025-04-17T05:53:20Z VATICAN CITY (AP) The Vatican on Thursday opened the most solemn period of Holy Week with a recovering Pope Francis largely on the sidelines, as cardinals were designated to take his place presiding over the most important liturgical services leading up to Easter.The 88-year-old Francis was a no-show at Holy Thursday Mass in St. Peters Basilica. But there were unconfirmed reports in the Italian media that he hoped to visit Romes central prison later in the day to keep an appointment he has maintained throughout his 12-year papacy: to commemorate Christs Last Supper before his crucifixion with the least fortunate.The Vatican declined to confirm or deny the reports, which stressed that any such outing would be private and depend on Francis condition. But it also seemed plausible, given Francis emphasis on ministering to prisoners, particularly during the 2025 Holy Year which both opened and will close with special papal events for inmates. Francis, who is recovering from a life-threatening bout of double pneumonia this winter, is expected to make at least some Easter appearances. He made a surprise cameo at the end of Palm Sunday Mass last weekend and in recent days has made some unannounced visits including one in which he wasnt dressed in his papal white cassock to pray in St. Peters Basilica and St. Mary Major basilica across town. By all indications he is continuing to improve after his five-week hospital stay and is slowly resuming some of his normal activities. In recent outings, he has been seen without the nasal tubes that provide supplemental oxygen and Vatican officials say he is increasingly less reliant on the therapy. Francis received medical workers who treated him On Wednesday, Francis held his first formal group audience since returning to the Vatican on March 23, meeting with the medical staff of the Gemelli hospital who cared for him during his 38-day stay. Gathered in a Vatican audience hall, Francis thanked the 70-plus doctors, nurses and administrators and asked them for their continued prayers.Thank you for everything you did, Francis said, his voice still labored but seemingly stronger as he continues respiratory and physical therapy. He gave special thanks to the rector of Gemellis affiliated Catholic University of the Sacred Heart, Elena Beccalli, whom he praised for her strong leadership. When women command, things go well, he said in his longest public remarks since his hospitalization.Francis has delegated the demanding Holy Week liturgical celebrations to hand-picked cardinals, but the Vatican says the pope himself composed the meditations that will be read aloud by others during the Via Crucis (Way of the Cross) procession on Friday night at Romes Colosseum.The Holy Thursday Mass, for example, during which the oils used in liturgical rituals throughout the year were blessed, was celebrated by the retired head of the Vaticans patrimony office, Cardinal Domenico Calcagno. Fridays solemn commemoration before the crucifixion of Christ was assigned to Cardinal Claudio Gugerotti, who heads the Vatican office in charge of eastern rite Catholics. Easter Sunday was assigned to the retired administrator of St. Peters, Cardinal Angelo Comastri. It remains to be seen how Francis will handle Easter Sundays traditional Urbi et Orbi (Latin for to the city and the world) speech and blessing after Mass. Normally the pope delivers a sometimes lengthy discourse on the state of the world from the loggia of St. Peters, and then imparts a special blessing to the faithful in the piazza below. In theory someone else could read the speech while Francis could impart the blessing. Francis was admitted to Gemelli on Feb. 14 with bronchitis that quickly developed into a life-threatening case of double pneumonia. Upon his release March 23, doctors prescribed two months of convalescence at the Vatican with daily respiratory and physical therapy to improve his breathing and vocal function. With time, they have predicted he will be able to resume his normal activities.___Associated Press religion coverage receives support through the APs collaboration with The Conversation US, with funding from Lilly Endowment Inc. The AP is solely responsible for this content.

Nature, Published online: 17 April 2025; doi:10.1038/d41586-025-01234-5Understanding the playbook that those in power use to twist numbers, and how they make others complicit, is only becoming more important in the post-truth world.

Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08861-yThe combined activation of Wnt and STAT3 signalling enables long-term self-renewal of human hepatocyte organoids, maintaining hepatic identity, supporting gene editing and offering therapeutic potential for liver disease through enhanced functionality, structure and metabolic competency.

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Supervisor of the Checklist for the State of New Hampshire Leslie Dombroski, left, registers Elise Collins, 18, to vote in Derry, N.H., Tuesday, March 11, 2025. (AP Photo/Reba Saldanha)2025-04-17T12:14:56Z NEW YORK (AP) A federal judge on Thursday will hear arguments in three cases from national Democrats and voting rights groups that are challenging President Donald Trumps recent executive order on elections, which, among other changes, would require proof of citizenship to register to vote in federal elections. The Democratic National Committee, the League of United Latin American Citizens, the League of Women Voters Education Fund and others are seeking to block Trumps sweeping overhaul of federal election processes, alleging that the changes he wants are unconstitutional. The Republican presidents executive order says the U.S. has failed to enforce basic and necessary election protections and calls on states to work with federal agencies to share voter lists and prosecute election crimes. It threatens to pull federal funding from states where election officials dont comply. It also aims to mandate major changes to election processes, including adding a proof-of-citizenship requirement to the federal voter registration form and requiring all mail ballots to be received, rather than just postmarked, by Election Day nationwide. The plaintiffs argue Trumps order is illegal because it asserts power that he does not have over an independent agency. That agency, the U.S. Election Assistance Commission, sets voluntary voting system guidelines and maintains the federal voter registration form. The plaintiffs also argue the order violates the Constitution, which says that states not the president get to decide the times, places and manner of how elections are run. The Constitutions so-called Elections Clause also gives Congress the power to make or alter election regulations, at least for federal office, but it doesnt mention any presidential authority over election administration.U.S. District Judge Colleen Kollar-Kotelly in Washington, D.C., will consider the plaintiffs pleas for a preliminary injunction, temporarily blocking the order as the lawsuits play out. She instructed the parties to be prepared to discuss a range of topics, including whether the Election Assistance Commission can comply with Trumps demands while following the law and whether the plaintiffs have standing to raise each of their claims. Justin Levitt, a former Justice Department attorney and a White House adviser during President Joe Bidens administration, said the Constitution is clear that the president has very little authority to regulate federal elections. But he said he expects the hearing will include debate over whether these groups have standing to sue and whether it is the appropriate time to bring a lawsuit.This is a pretty easy case when it comes to the legal merits, but whether they get to the legal merits is not trivial, he said.The hearing comes as other lawsuits against Trumps executive order are pending.Earlier this month, 19 Democratic attorneys general asked the court to reject Trumps executive order. The following day, Washington and Oregon, two states that hold all-mail elections, followed up with their own lawsuit against the order. ___Associated Press writer Christina A. Cassidy in Atlanta contributed to this report.___The Associated Press receives support from several private foundations to enhance its explanatory coverage of elections and democracy. See more about the APs democracy initiative here. The AP is solely responsible for all content. ALI SWENSON Swenson covers politics and the information landscape for The Associated Press. She is based in New York. twitter

Esta combinacin de fotografas proporcionada por el Departamento de Prisiones de California muestra a Erik (izquierda) y Lyle Menendez. (Departamento de Prisiones de California va AP, Archivo)2025-04-17T04:01:49Z LOS ANGELES (AP) Erik and Lyle Menendez could learn this week whether theyll get reduced sentences and the chance for freedom nearly 30 years after they were convicted of murdering their parents.A Los Angeles judge will preside over the resentencing hearing expected to last two days starting Thursday. The judge could make a verbal decision during the hearing or rule later with a written decision. If he shortens their sentences, the brothers would still need approval from the states parole board to get out of prison.They were sentenced in 1996 to life in prison without the possibility of parole for murdering their entertainment executive father Jose Menendez and mother Kitty Menendez in their Beverly Hills home in 1989. The brothers were 18 and 21 at the time of the killings. While defense attorneys argued the brothers acted out of self-defense after years of sexual abuse by their father, prosecutors said the brothers killed their parents for a multimillion-dollar inheritance. The case has captured the publics attention for decades, and the Netflix drama Monsters: The Lyle and Erik Menendez Story and documentary The Menendez Brothers have been credited with bringing new attention to the case. Supporters of the brothers have flown in from across the country to attend rallies and hearings in the past few months. The resentencing hearing will center on whether the brothers have been rehabilitated in prison and deserve a lesser sentence of 50 years to life. That would make them eligible for parole under Californias youthful offender law because they committed the crime under the age of 26. Former Los Angeles District Attorney George Gascn asked a judge last year to reduce the brothers sentences. He lost reelection to Nathan Hochman, who moved to withdraw the resentencing request and has argued the brothers have not taken full responsibility for their crimes. A resentencing petition laid out by Gascn focuses on the brothers accomplishments and rehabilitation. The brothers attorneys say their clients have worked hard over the decades to better themselves and give back to the prison community. The extended Menendez family, with the exception of an uncle who died last month, has said they fully forgive the brothers for what they did and want them to be freed. With Hochman in charge, prosecutors argued last Friday they could not support the brothers resentencing. Los Angeles County Superior Court Judge Michael Jesic ruled the resentencing hearings could continue despite their opposition.Prosecutors have said the brothers have not admitted to lies told during their trial about why they killed their parents, or that they asked their friends to lie for them in court. Hochmans office has also said it does not believe that the brothers were sexually abused by their father and that by speaking about their childhood abuse, they have not taken complete responsibility for the crime.

Nature, Published online: 16 April 2025; doi:10.1038/d41586-025-01158-0The construction of a pangenome sequence collection that incorporates the genomes of nearly 150 wild and cultivated rice varieties captures all the genetic diversity found in this plant. It reveals genes associated with disease resistance that are unique to wild rice, and provides insights into the origins of domesticated rice.

Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08700-0After transplantation into the brain of patients with Parkinsons disease, allogeneic dopaminergic progenitors derived from induced pluripotent stem cells survived, produced dopamine and did not form tumours, therefore suggesting safety and potential clinical benefits for Parkinsons disease.

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Acting interior minister Sirajuddin Haqqani, speaks during the funeral prayers of Khalil Haqqani, the minister for refugees and repatriation, during his funeral procession in eastern Paktia province, Afghanistan, Dec. 12, 2024. (AP Photo/Saifullah Zahir, File)2025-04-17T12:51:01Z MOSCOW (AP) Russias Supreme Court on Thursday lifted a ban on Afghanistans ruling Taliban, a group that was designated as a terrorist organization more than two decades ago.The move was a diplomatic victory for the Taliban, who were put on Russias list of terrorist organizations in 2003, making any contact with them punishable under Russian law.At the same time, Taliban delegations have attended various forums hosted by Russia as Moscow has sought to position itself as a regional power broker.The courts ruling on a request by the Prosecutor Generals Office followed last years adoption of a law stipulating that the official designation as a terrorist organization could be suspended by a court.The former Soviet Union fought a 10-year war in Afghanistan that ended with Moscow withdrawing its troops in 1989.Russian officials have recently been emphasizing the need to engage with the Taliban to help stabilize Afghanistan. In recent years, the Central Asian nations of Kazakhstan and Kyrgyzstan have removed the Taliban from their lists of terrorist groups. The Taliban seized power in Afghanistan in August 2021 as U.S. and NATO troops were in the final weeks of withdrawing from the country after two decades of war. The Taliban initially promised a more moderate rule than during their first stint in power from 1996 to 2001, but started to enforce restrictions on women and girls soon after the 2021 takeover. Women are barred from most jobs and public places, including parks, baths and gyms, while girls are banned from education beyond sixth grade. Such measures have isolated the Taliban on the world stage, although their government has established diplomatic ties with countries including China and the United Arab Emirates.The U.N. this year renewed its call for the Taliban to lift the bans.The groups decrees limiting the participation of girls and women have affected foreign aid to the country. The Taliban also have brought back their strict interpretation of Islamic law, or Shariah, including public executions. Some Taliban want greater engagement with the international community and want to scrap harsher policies to attract more outside support. In recent months, there has been increased engagement between the Taliban and the U.S. under President Donald Trump, mostly because of prisoner exchanges and releases.Ibraheem Bahiss, a senior analyst with Crisis Groups Asia Program, said the Talibans listing as a terrorist group was a legal impairment for trade and political ties with Kabul and its lifting reflected Moscows desire to improved relations. However, beyond making it easier for individuals and businesses to engage with Afghanistan. I am not sure what other major benefit this will have, he said.South Asia analyst Michael Kugelman said the Russian move was not ground-breaking because many countries had never formally designated the Taliban as a terrorist organization. At the same time, he called the decision a win-win for bilateral relations. For Russia, he said it would serve as a confidence-building measure helping pave the way for more engagement and enabling Moscow to better protect its interests in Afghanistan, particularly concerns about anti-Russia terror groups like Islamic State-Khorasan. Meanwhile, for the Taliban, the court decision is a legitimacy-boosting outcome they can leverage to point to international acceptance of their rule, Kugelman observed.___Associated Press writer Riazat Butt contributed to this report from Islamabad.

This image provided by World Press Photo and taken by Samar Abu Elouf, for The New York Times, won the World Press Photo Award of the Year and shows Mahmoud Ajjour (9), who was injured during an Israeli attack on Gaza City in March 2024, finds refuge and medical help in Doha, Qatar, 28 June 2024. (Samar Abu Elouf, for The New York Times/World Press Photo via AP)2025-04-17T10:03:46Z THE HAGUE, Netherlands (AP) A portrait of a young Palestinian boy who lost both arms as a result of an Israeli attack in Gaza was honored Thursday as World Press Photo of the year.The photo, taken by Qatar-based Palestinian photographer Samar Abu Elouf for The New York Times shows 9-year-old Mahmoud Ajjour with his arms missing just below each shoulder.One of the most difficult things Mahmouds mother explained to me was how when Mahmoud first came to the realization that his arms were amputated, the first sentence he said to her was, How will I be able to hug you? Abu Elouf said in a statement released by the World Press Photo organization.The winner of the 68th edition of the prestigious photojournalism contest was selected from 59,320 entries submitted by 3,778 photographers from 141 countries.This is a quiet photo that speaks loudly. It tells the story of one boy, but also of a wider war that will have an impact for generations, said World Press Photo Executive Director Joumana El Zein Khoury. In a statement, the organization said that Ajjour was injured while fleeing an Israeli attack in March 2024. After he turned back to urge his family onward, an explosion severed one of his arms and mutilated the other, according to the World Press Photo citation.This young boys life deserves to be understood, and this picture does what great photojournalism can do: provide a layered entry point into a complex story, and the incentive to prolong ones encounter with that story, said jury chair Lucy Conticello, who is Director of Photography for French newspaper Le Mondes weekend magazine. Winning photographer Abu Elouf was evacuated from Gaza in December 2023 and she now lives in the same apartment complex as Ajjour in Qatars capital, Doha.Israel launched its devastating attack on Gaza after Hamas Oct. 7, 2023 attack, in which thousands of militants stormed into southern Israel from Gaza, killing some 1,200 people, mostly civilians, and abducting 251. The Palestinian Health Ministry in Gaza says over 51,000 Palestinians have been killed in the Israeli offensive. It does not differentiate between civilians and militants, but says that over half of the dead were women and children, including at least 876 infants under 1. It says over 116,000 people have been wounded.Israel blames Hamas for the heavy civilian toll because the group carries out attacks and other military activities from residential areas and civilian buildings.Competition organizers also named two World Press Photo finalists that highlighted the issues of migration and climate change.A dark photo by John Moore for Getty Images shows Chinese migrants warming themselves after crossing the U.S.-Mexico border, and a picture by Musuk Nolte for Panos Pictures, Bertha Foundation, of a young man carrying food across a dried up river bed in Brazils Amazon basin region.In regional results announced earlier by the World Press Photo Foundation, The Associated Press was among winners in the Asia-Pacific and Oceania region. Photographer Jae C. Hong won in the Singles category with an image titled Korea Adoption Fraud and Noel Celis won in the Stories category for photos from the Philippines titled Four Storms, 12 Days.

Nature, Published online: 17 April 2025; doi:10.1038/d41586-025-01191-zModels estimate the ginormous potential impact of foreign-aid cuts.

Nature, Published online: 17 April 2025; doi:10.1038/d41586-025-01014-1Conventional tests that look only at a small subset of genetic code often miss variations hiding outside the protein-coding genome.

Two boats collided during a fishing tournament in Alabama, killing three people, officials said.

ESPN analyst Lee Corso, widely known for his headgear picks and "not so fast, my friend" retort, will retire from "College GameDay" in August.

Spring buds appear on a tree near Eliot House, rear, at Harvard University, Tuesday, April 15, 2025, in Cambridge, Mass. (AP Photo/Charles Krupa)2025-04-17T14:17:43Z WASHINGTON (AP) President Donald Trumps administration has escalated its ongoing battle with Harvard, threatening to revoke the universitys ability to host international students as the president called for withdrawing Harvards tax-exempt status.The Department of Homeland Security ordered Harvard late Tuesday to turn over detailed records of its foreign student visa holders illegal and violent activities by April 30. International students make up 27% of the campus.The department also said it was canceling two grants to the school totaling $2.7 million. The moves deepen the crackdown on Harvard, which on Monday became the first university to openly defy the administrations demands related to activism on campus, antisemitism and diversity. The federal government has already frozen more than $2 billion in grants and contracts to the Ivy League institution. Trump suggested Tuesday on social media that Harvard should lose its tax-exempt status if it keeps pushing political, ideological, and terrorist inspired/supporting Sickness?The hold on federal money for research at Harvard marked the seventh time the administration has taken such a step at one of the nations most elite colleges. The government is attempting to force compliance with Trumps political agenda at schools he accuses of pushing woke policies and allowing antisemitism to fester. In a letter to Harvard on Friday, Trumps administration called for broad government and leadership reforms at the university, plus changes to its admissions policies. It also demanded that the university audit views of diversity on campus and stop recognizing some student clubs. Harvard President Alan Garber said Monday that the university would not bend to the governments demands. Later that day, the White House announced the freeze of more than $2.2 billion in multi-year grants and $60 million in contracts. Conservative strategist Christopher Rufo said the government should respond to Harvards defiance by cutting all federal money and stripping nonprofit status at Harvard and other Ivies that defy federal orders. Rufo urged the government to use the same tools it used during the Civil Rights Movement to force desegregation.Trump needs to follow through on his threat to defund one of the Ivy League universities, Rufo said on social media Tuesday. Cut the funding and watch the university implode.Rufo said Harvard has discriminated against white and Asian American students, citing events such as graduation celebrations specific to certain ethnic groups, along with a 2021 theater performance exclusively for Black-identifying audience members.For the Trump administration, Harvard presents the first major hurdle in its attempt to force change at universities that Republicans say have become hotbeds of liberalism and antisemitism.Trumps campaign started at Columbia University, which initially agreed to several demands from the Trump administration but took a more emboldened tone after Harvards defiance. Columbias acting president, Claire Shipman, said in a campus message Monday that some of the demands are not subject to negotiation and that she read of Harvards rejection with great interest. Trump has targeted schools accused of tolerating antisemitism amid a wave of pro-Palestinian protests on U.S. campuses. Some of the governments demands touch directly on that activism, calling on Harvard to impose tougher discipline on protesters and to screen international students for those who are hostile to the American values.___The Associated Press education coverage receives financial support from multiple private foundations. AP is solely responsible for all content. Find APs standards for working with philanthropies, a list of supporters and funded coverage areas at AP.org. ANNIE MA Ma is an Associated Press national writer who covers K-12 education. twitter mailto JOCELYN GECKER Gecker is an Associated Press reporter covering education with a focus on social media and youth mental health. twitter mailto COLLIN BINKLEY Binkley covers the U.S. Education Department and federal education policy for The Associated Press, along with a wide range of issues from K-12 through higher education. twitter mailto

In this photo, provided by the Ukrainian Emergency Service, firefighters extinguish fire following a Russian attack in Dnipro, Thursday, April 17, 2025. (Ukrainian Emergency Service via AP)2025-04-17T09:43:11Z KYIV, Ukraine (AP) Russian forces launched a massive drone attack on the southeastern Ukrainian city of Dnipro, killing three people including a child and wounding dozens, officials said Thursday.The strike was the latest in a string of Russian attacks that have caused civilian casualties and intensified in recent weeks, as the United States continues efforts to negotiate a ceasefire between Moscow and Kyiv.Thirty people, including five children, were wounded in the attack, said Serhii Lysak, head of the Dnipropetrovsk regional administration.Local authorities said the drones caused widespread damage to civilian infrastructure, including an educational institution, a dormitory, a gymnasium and multiple residential buildings. Emergency Service said the strikes triggered multiple fires across the city.In reaction to the Dnipro attack, Ukraines President Volodymyr Zelenskyy urged allies to support the country with air defense weapons. Every defense package from partners for Ukraine now, every form of support from the world for our resilience, is literally protecting lives, Zelenskyy wrote on Telegram Thursday. Russia uses every day and every night to kill. Meanwhile, a Ukrainian delegation was in Paris for a round of bilateral and multilateral meetings with representatives of countries from the coalition of the willing, including France, Germany and the United Kingdom, said Andrii Yermak, head of the Presidential Office. The multinational force is expected to act as a long-term security guarantee aimed at deterring future Russian aggression after a ceasefire is in place. The delegation also includes Foreign Minister Andrii Sybiha and Defense Minister Rustem Umerov. Yermak said talks with representatives of the United States are also scheduled.We are working on important aspects for the security of Ukraine and all of Europe, Yermak wrote on Telegram. Separately, Russias Defense Ministry said Thursday that its air defense systems shot down 71 Ukrainian drones overnight across six regions. Of those, 49 drones were intercepted over the Kursk region, which borders Ukraine, it said. Kyivs forces seized a strip of land in the area during a surprise incursion in August 2024.Additional drones were downed over the Bryansk, Vladimir, Oryol, Ryazan, and Tula regions, the ministry said.And in Ukraine, Russia launched five missiles along with 75 strike drones overnight, the air force said Thursday. Air defense forces destroyed 25 drones, while another 30 were jammed.___Follow APs coverage of the war in Ukraine at https://apnews.com/hub/russia-ukraine

Palantir, the surveillance giant, is taking on an increased role with Immigration and Customs Enforcement (ICE), including finding the physical location of people who are marked for deportation, according to Palantir Slacks and other internal messages obtained by 404 Media.The leak shows that Palantirs work with ICE includes producing leads for law enforcement to find people to deport and keeping track of the logistics of Trumps mass deportation effort, and provides concrete insight into the Trump administrations wish to leverage data to enforce its immigration agenda. The internal communications also show Palantir leadership preparing for a potential backlash from employees or outsiders, with them writing FAQs that can be sent to friends or family that start to ask about Palantirs work with ICE.Hey all, wanted to provide a quick update on our work with ICE, Akash Jain, the Chief Technology Officer of Palantir Technologies and President of Palantir USG, wrote in a Slack message several days ago. Over the last few weeks we prototyped a new set of data integrations and workflows with ICE.Do you work at Palantir? I would love to hear from you. Using a non-work device, you can message me securely on Signal at joseph.404 or send me an email at joseph@404media.co.The new administrations focus on leveraging data to drive enforcement operations has accelerated those efforts, Jain wrote.A page of an internal Palantir wiki obtained by 404 Media says Palantir participated in a three-week sprint, where developers rapidly work on new projects, with Homeland Security Investigations (HSI) Innovation Lab, which is the agencys centralized hub for developing new advanced analytics capabilities and tools. The primary focus of that sprint was providing immigration agents with improved awareness about the criminality and location of individuals who have already received a final order of removal, the wiki says.That prototype was a success, and ICE updated an ongoing Palantir contract for the company to continue work on the project, the wiki says. The wiki says the project is related to Enforcement Prioritization and Targeting, and specifically to support the development of an accurate picture of actionable leads based on existing law enforcement datasets to allow law enforcement to prioritize enforcement actions.404 Media first broke news of Palantirs updated ICE contract on Wednesday. U.S. government contracting records said Palantir was paid tens of millions of dollars to deploy the new targeting and enforcement prioritization, and another record said Palantir was working on complete target analysis of known populations. Those additions, worth tens of millions of dollars, were added to Palantirs $95.9 million contract with ICE for work on the Investigative Case Management (ICM) system, a powerful database and search tool the agency uses.The leaked material contains more specifics on that work. Palantirs role also includes a self-deportation tracking project, which is designed to help ICE develop a more accurate understanding of people who voluntarily leave the United States, and another project concerning immigration lifecycle operations which will support the logistics of deportation, such as overlaying information about detained or removed individuals and the availability of transportation resources, according to the wiki.This effort will last around six months and is concentrated on delivering prototype capabilities, the wiki says. The wiki leaves open the potential for longer term engagements with ICE, saying that is currently to be determined and we will aim to provide additional periodic updates as the situation develops.Neither Palantir nor ICE immediately responded to 404 Medias requests for comment.In the wiki, Palantir says it continues to support HSIs transnational criminal investigative mission, which can include countering human and drug trafficking. The initial coding sprint came about after HSI sunsetted a tool based on Palantirs Gotham product with nearly 3,700 users in late 2022, developed its own in-house system called RAVEn, then came back to Palantir in late 2024 after that project failed, the wiki says. By March 2025, because of the Trump administrations focus on immigration and a new sense of urgency according to Palantir, the HSI leadership team sought our assistance to accelerate mission progress across the agency, the wiki says.Palantir writes it remains committed to privacy and civil liberty protections, and says it believes this work with ICE is intended to promote government efficiency, transparency, and accountability.We believe these conditions are the necessary predicate to provide the tools to help ICE drive accurate enforcement actions and enable fair treatment and legal protections (including due process) for citizens and non-citizens, the wiki says.Palantir is cognizant of the risks to privacy and civil liberties involved in these mission sets and how they may be influenced by shifts in priorities, another section reads. Many risks will not be within our means to addresssome are structural and must be fully baked into the equation by virtue of a willingness to engage at all in these efforts. It's important to note that there will be failures in the removal operations process, it adds.The Trump administration has deported more than 200 people it says are hardened criminals to an El Salvadoran mega prison with no due process. A CBS News 60 Minutes investigation found that 75 percent of the men deported had no apparent criminal record. As part of that, the U.S. deported Abrego Garcia to the foreign prison: A government lawyer has said Garcias deportation was an administrative error, and despite the Supreme Court ruling that the government must facilitate Garcias return, President Trump and El Salvadoran President Bukele have deflected when asked if they will do so. On Wednesday the Department of Justice released documents to support its targeting of Garcia.President Trump has also called for deporting U.S. citizens to El Salvador.On top of the El Salvador prison deportations, the Trump administration has revoked the visas of hundreds of students, many under the pretence that they engaged in antisemitism or supported Hamas. Plainclothes officers picked up a student on the street for deportation despite the State Department finding no evidence she was linked to Hamas or antisemitism; the justification used was an op-ed she co-wrote criticizing Israels disproportionate level of violence in Gaza. ICE agents arrested a green card holding student who participated in college protests at his interview to become a U.S. citizen. A judge recently ruled that Columbia University activist Mahmoud Khalil, who was among the first students arrested by ICE, can be deported.Palantir's language about fair treatment and legal protections inverts the reality unfolding before us: government agents abducting a Columbia student and permanent resident at his citizenship interview, and deporting a Maryland father to a prison overseen by a dictator, despite courts deciding he could stay and compelling the government not to remove him, Laura Rivera, an attorney at Just Futures Law, told 404 Media in an email.Palantir distorts the truth to obscure its complicity in carrying out an authoritarian agenda, supplying one of the world's most powerful domestic surveillance agencies with tools to enable their mass surveillance not only of immigrants, but of all of us, she added.In its wiki Palantir says the national conversation around immigration has shifted, with both parties campaigning on the issue. With this, there is both a lot of opportunity to do good work, as well as risk of potential harm, the wiki says.In the leaked Slack messages, Jain said that Palantir was working to include updates about this work into an FAQ with the companys PCL, or Privacy and Civil Liberties team. Jain said the company will also hold discussion groups about the topic.I recognize this is a topic of interest for a lot of hobbits and were working to integrate these updates into the PCL FAQ, Jain added, with hobbits a likely reference to J. R. R. Tolkiens The Lord of the Rings, which Palantir gets its name from.We recognize as this becomes more public you will probably be asked about whats fact vs. fiction from friends, family, candidates and customers, Jain wrote, adding that the company is working on another FAQ that could be shared externally in those situations.John Grant, Palantirs Ethics Education Program Lead, posted links to some internal pages that might help people think through some of the questions this work might raise for you. They were:Ethics FAQ - Can it be right to support a customer who you think is wrong?Ethics Discussion - The Ethics of ImmigrationJain added that the small group discussions will likely be organized locally in each office or business area.Palantir is currently running adverts at U.S. colleges which say a moment of reckoning has arrived for the West. Our culture has fallen into shallow consumerism while abandoning national purpose. Too few in Silicon Valley have asked what ought to be builtand why. We did.Acting ICE Director Todd Lyons said at the recent Border Security Expo that his intention for the agency is squads of trucks detaining immigrants in a similar way to how Amazon trucks are around the country delivering packages, the Arizona Mirror reported.The wiki says Palantir has developed into a more mature partner for ICE.

Nature, Published online: 17 April 2025; doi:10.1038/d41586-025-01242-5Henry Sila Nzioki has developed a weed-killing fungus to improve food security.

Nature, Published online: 17 April 2025; doi:10.1038/s41586-025-08977-1Author Correction: Continued Atlantic overturning circulation even under climate extremes

Bill Stampfl vanished climbing Peru's highest mountain 22 years ago. This is the story of the hiker who found him and brought closure to Stampfl's family.

Gabriel Martinelli was ecstatic to follow in the footsteps of Arsenal legend Thierry Henry by scoring at the Bernabe in Wednesday's 2-1 win at Real Madrid.

by Christopher Bing and Avi Asher-Schapiro ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as theyre published. Four days before Donald Trumps inauguration, financial technology startup Ramp published a pitch for how to tackle wasteful government spending. In a 4,000-word blog post titled The Efficiency Formula, Ramps CEO and one of its investors echoed ideas similar to those promoted by Trump and his billionaire ally Elon Musk: Federal programs were overrun by fraud, and commonsense business techniques could provide a quick fix.Ramp sells corporate credit cards and artificial intelligence software for businesses to analyze spending. And while the firm appears to have no existing federal contracts, the post implied the government should consider hiring it. Just as Ramp helped businesses manage their budgets, the company could do the same for a variety of government agencies, according to the blog and company social media posts.It didnt take long for Ramp to find a willing audience. Within Trumps first three months in office, its executives scored at least four private meetings with the presidents appointees at the General Services Administration, which oversees major federal contracting. Some of the meetings were organized by the nations top procurement officer, Josh Gruenbaum, commissioner of the Federal Acquisition Service.GSA is eying Ramp to get a piece of the governments $700 billion internal expense card program, known as SmartPay. In recent weeks, Trump appointees at GSA have been moving quickly to tap Ramp for a charge card pilot program worth up to $25 million, sources told ProPublica, even as Musks Department of Government Efficiency highlights the multitudes of contracts it has canceled across federal agencies.Founded six years ago, Ramp is backed by some of the most powerful figures in Silicon Valley. One is Peter Thiel, the billionaire venture capitalist who was one of Trumps earliest supporters in the tech world and who spent millions aiding Vice President JD Vances Ohio Senate run. Thiels firm, Founders Fund, has invested in seven separate rounds of funding for Ramp, according to data from PitchBook. Last year Thiel said there was no one better positioned to build products at the intersection of AI and finance.To date, the company has raised about $2 billion in venture capital, according to startup tracking website Crunchbase, much of it from firms with ties to Trump and Musk. Ramps other major financial backers include Keith Rabois of Khosla Ventures; Thrive Capital, founded by Joshua Kushner, the brother of Trumps son-in-law Jared Kushner; and 8VC, a firm run by Musk allies. The special attention Gruenbaum paid to Ramp raised flags inside and outside the agency. This goes against all the normal contracting safeguards that are set up to prevent contracts from being awarded based on who you know, said Scott Amey, the general counsel with the bipartisan Project on Government Oversight. He said career civil servants should lead the process to pick the best choice for taxpayers.A senior GSA official, who requested anonymity for fear of retribution, said the high level attention Ramp received was unusual, especially before a bid had been made public. You dont want to give this impression that leadership has already decided the winner somehow.GSA told ProPublica it refutes any suggestion of unfair or preferential contracting practices, with a spokesperson adding that the credit card reform initiative has been well known to the public in an effort to address waste, fraud, and abuse.Ramp did not respond to requests for comment.Rabois, one of Ramps earliest investors, is part of an influential group of tech titans known as the PayPal Mafia. Leaders of the early payments company include several influential players surrounding the Trump administration, including Musk and Thiel. Rabois and his husband, Jacob Helberg, hosted a fundraiser that pulled in upwards of $1 million for Trumps 2024 campaign, according to media reports. Trump has nominated Helberg for a senior role at the State Department.Rabois sits on Ramps board of directors. He has said he had no plans to join the Trump administration, instead telling CNBC: I have ideas, I can spoon-feed them to the right people. He told ProPublica his comments to CNBC were about big-picture policy ideas and that he had no involvement in any government-related initiatives for the company. Ramp could be a great choice for any government that wants to improve its efficiencies, Rabois added.Helberg said he has no involvement in anything related to Ramp whatsoever.Thrive Capital, Kushners firm, did not respond to a request for comment. A spokesperson for Thiel did not provide a comment. 8VC did not respond to a request for comment, nor did the White House or Musk; previously, Musk has said Ill recuse myself if conflict-of-interest issues arise.Ramps meetings with Gruenbaum who comes from private equity firm KKR and has no prior government experience came at an opportune moment. GSA will decide by years end whether to extend the SmartPay contract, and preparations are afoot for the next generation of the program. SmartPay has been worth hundreds of millions of dollars in fees for the financial institutions that currently operate it, U.S. Bank and Citibank.Gruenbaum and acting GSA administrator Stephen Ehikian entered the agency with a strong belief that SmartPay and other government payment programs were rife with fraud or waste, causing huge losses, sources within GSA say an idea echoed in Ramps January memo.Yet both GOP and Democratic budget experts, as well as former GSA officials, describe that view as ill-informed. SmartPay, which provides Visa and Mastercard charge cards to government employees, enables the federal workforce to purchase office supplies and equipment, book travel and pay for gas.The cards typically are used to fund travel and purchases up to $10,000.SmartPay is the lifeblood of the government, said former GSA commissioner Sonny Hashmi, who oversaw the program. Its a well-run program that solves real world problems with exceptional levels of oversight and fraud prevention already baked in.Jessica Riedl, a GOP budget expert at the conservative Manhattan Institute think tank, said the notion that there was significant fraud in the charge card technology was far-fetched. She had criticized waste in government credit card programs before the latest SmartPay system was implemented in 2018.This was a huge problem about 20-25 years ago, she said. In the past 15 years, there have been new controls put into government credit card purchases.A 2017 audit of the program by the Government Accountability Office concluded there was little evidence of potential fraud in SmartPay small purchases, though it found documentation errors. More recent government audits found some instances where officials did not always use anti-fraud tools.GSAs new leaders are convinced SmartPay is entirely broken, a view they shared in private meetings, sources said. In February, they put a temporary $1 limit on government cards and severely restricted the number of cardholders, choking off funds to workers in the field.Chaos ensued across the government, news organizations reported: Staff at the National Institutes of Health were reportedly unable to purchase materials for experiments, Federal Aviation Administration workers worried they would be unable to pay for travel to test systems in the field, and National Park Service employees could not travel to oversee road maintenance projects.At the time, GSA released a statement saying the limitations were risk mitigation best practice and internally began moving to revamp SmartPay.$25 Million OpportunityRamps first bite of the SmartPay business could come through a pilot program worth up to $25 million that GSA announced several weeks after agency leadership began meeting with the company.At the tail end of the Biden administration, GSA had sent out a request for information, or RFI, seeking industry input about how to improve the next iteration of SmartPay. But some industry players who submitted responses said they did not hear back from the government. Instead, GSA started meeting with Ramp.GSA put out a new RFI for the pilot program on March 20, 2025, leaving it open for less than seven business days.John Weiler, co-founder of the nonprofit research group the IT Acquisition Advisory Council, said such a short window appeared unusual. A week is nothing, it gives the impression they had already picked the winner, said Weiler, who has worked with Republican Sen. Chuck Grassley to investigate IT contracting issues.Ramp is the clear-cut favorite, to secure this work, one source inside GSA and another former official told ProPublica. The winner has not yet been announced.Procurement experts told ProPublica that consulting with industry leaders before a major overhaul is good practice but that the fact-finding process must be evenhanded and led by professional contracting officers.The GSA spokesperson said that any and all communications with potential vendors, of which there were multiple, has been a part of market research in order to provide the best solution for American taxpayers. The agency declined to answer questions about whether Ramp had already been chosen internally for SmartPay work.The pilot program is unique because it uses a special GSA purchasing authority known as commercial solutions opening. This process has been used by the Pentagon to help speed up the acquisition of products for fighters in armed conflict zones. The designation means the chosen contractor can be selected faster and without the same level of controls.Its not clear how Ramp originally secured private meetings with GSA leaders. Nor is it clear if Ramp will ultimately take over the entire SmartPay contract from Citibank and U.S. Bank. Spokespeople for U.S. Bank and Citibank declined to comment.It is clear that Ramp has never had a client like the federal government. The only public-sector partner listed on its webpage is a charter school network in Nashville, Tennessee.Still, even before the RFI was publicly announced, Ramp had begun reaching out to contacts in the payment industry asking about the special bank identification numbers required to process government payments, said an industry source. Such steps, two former GSA officials said, were another sign that Ramp was preparing to work on the program.Ramps meetings with GSA come as the agency is poised to take on a more significant role in spending decisions across government. The same day the SmartPay pilot was announced, Trump issued an executive order that seeks to centralize much of government procurement inside of GSA. The DOGE initiative has been effectively headquartered out of the agency staffers have installed beds and dressers for overnight stays in the building, and Musks right-hand man Steve Davis is a key adviser to the agencys leadership.The SmartPay contract negotiation has so far flown under the radar. But changes to the credit card program could further transform daily life for federal employees and fundamentally change how agencies operate. It also represents a giant business opportunity.Theres a lot of money to be made by a new company coming in here, said Hashmi, the former GSA official. But you have to ask: What is the problem thats being solved? Doris Burke contributed research.

Headlights illuminate cobblestone streets in Old San Juan, Puerto Rico, during an island-wide blackout, Wednesday, April 16, 2025. (AP Photo/Alejandro Granadillo)2025-04-17T15:28:45Z SAN JUAN, Puerto Rico (AP) An island-wide blackout hit Puerto Rico this week, leaving 1.4 million customers without power and more than 400,000 without water.It was the second massive outage to hit Puerto Rico since New Years Eve, when a blackout left 90% of clients without power.Crews on Thursday scrambled to restore power as a growing number of Puerto Ricans called on the governor to cancel the contracts of two companies that oversee the generation, transmission and distribution of power on the U.S. territory of 3.2 million residents. When did the blackout occur?At 12:38 p.m. on Wednesday, massive generating plants began to shut down across Puerto Rico after a transmission line failed.Refrigerators stopped humming, air conditioners fell silent and traffic lights went dark.People started realizing the magnitude of the outage when they began calling friends and family that live on the other side of the island who said that they, too, were without power.Hundreds of businesses closed, including the biggest mall in the Caribbean. Hospitals and the main international airport began running on generators while dozens of passengers using a rapid transit system that serves the capital, San Juan, were forced to walk on an overpass next to the trains rails to evacuate. Incredulous, Puerto Ricans began demanding answers from the government as crews scrambled to find out what happened. When are we going to do something? reggaeton superstar Bad Bunny wrote on X, reflecting peoples collective rage.Anger grew as people began posting pictures of those affected by the blackout, including one of a woman who had plugged a small machine into the outlet of a grocery store to give herself medical treatment for a lung condition. Why did it occur?Authorities are still investigating the causes of the blackout. One possibility is that overgrown vegetation may have affected the grid and caused a transmission line to fail, officials said.Luma Energy, the company responsible for overseeing transmission and distribution of power in Puerto Rico, is supposed to do frequent air patrols over certain lines to ensure they remain free of vegetation.Pedro Melndez, a Luma engineer, said in a news conference Thursday that he did not immediately have details on when the company last did an air patrol, but added that those occur with the frequency established in its contract.Josu Coln, the islands energy czar and former executive director of Puerto Ricos Electric Power Authority, said Luma also needs to explain why all the generators shut down after there was a failure in the transmission system, when only one was supposed to go into protective mode.Itll likely take weeks to find a precise reason for the blackout, although Gov. Jenniffer Gonzlez said Thursday that she expects to have a very preliminary report within three days. Why is Puerto Ricos power grid in such bad shape?For decades, Puerto Ricos Electric Power Authority did not give the grid the maintenance and investment it required.It began crumbling throughout the years, and then on Sept. 20, 2017, Hurricane Maria hit the U.S. territory as a powerful Category 4 storm. It snapped power lines, toppled transmission towers and broke flimsy wooden light posts, leaving some people nearly a year without power.In the months that followed, crews focused on emergency repairs. It wasnt until a couple years after the hurricane that actual reconstruction began.In June 2021, the Electric Power Authority contracted Luma as it struggled to restructure its more than $9 billion debt, with negotiations still ongoing.In January 2023, the authority contracted Genera PR to oversee the generation of power on the island as part of another public-private partnership.Puerto Rico has been plagued by chronic power outages since Maria, with pictures and videos of transmission lines on fire becoming increasingly common.Gonzlez has said that providing consistent energy is a priority and distanced herself from renewable energy goals set by the previous governor.Her administration recently extended the operations of Puerto Ricos lone coal-fired plant. Meanwhile, with a poverty rate exceeding 40%, many on the island cannot afford solar panels or generators.Roughly 117,000 homes and businesses on the island have solar rooftops. Petroleum-fired power plants provide 62% of Puerto Ricos power, natural gas 24%, coal 8% and renewables 7%, according to the U.S. Energy Information Administration.What are officials doing to improve the grid?A growing number of Puerto Ricans have demanded that the governor cancel Lumas contract, and she has pledged to do so.People must be fed up with us having such a mediocre system. If its not the transmission, its the generation, Gonzlez said. Of course there will be consequences.However, she noted that canceling the contract and finding a new company takes time.Officials also previously warned that there would not be sufficient generation come summer, when demand peaks. Given that concern, Gonzlez said the government is seeking to contract a company that can provide more than 800 megawatts of energy in the upcoming months. The request-for-proposal process began on March 25 and ends this month. Sixty companies have submitted proposals.____Follow APs coverage of Latin America and the Caribbean at https://apnews.com/hub/latin-america

Chair of the Board of Governors of the Federal Reserve System Jerome Powell speaks during an event hosted by the Economic Club of Chicago, Wednesday, April 16, 2025, in Chicago. (AP Photo/Erin Hooley)2025-04-17T12:14:08Z Follow live updates on President Donald Trump and his administration WASHINGTON (AP) President Donald Trump slammed Federal Reserve Chair Jerome Powell on Thursday, reiterating his frustration that the Fed has not aggressively cut interest rates and saying that the central bank leaders termination cannot come fast enough.Trump hinted at moving to fire Powell, whose term does not expire until May 2026. The Republican presidents broadside comes a day after Powell signaled that the Fed will keep its key interest rate unchanged while it seeks greater clarity on the impact of policy changes in areas such as immigration, taxation, regulation and tariffs.Powell also reiterated that Trumps tariffs would likely raise inflation and slow the economy, which could make it harder for the Fed to cut rates anytime soon. The Fed chair also suggested that the central bank will focus on fighting inflation in the wake of the tariffs, even if the duties did weaken the economy. Powells comments contributed to a drop in stock prices Wednesday. Oil prices are down, groceries (even eggs!) are down, and the USA is getting RICH ON TARIFFS, Trump said in a social media post. Referring to the European Central Bank, he added that Powell should have lowered Interest Rates, like the ECB, long ago, but he should certainly lower them now. Powells termination cannot come fast enough! AP AUDIO: Trump gripes about interest rates and says Fed Chair Powells termination cannot come fast enough AP Washington correspondent Sagar Meghani reports President Trump is showing more frustration with Fed chair Jerome Powell over interest rates. The European Central Bank on Thursday lowered its key interest rate from 2.5% to 2.25%. Powell was initially nominated by Trump in 2017, and he was appointed to another four-year term by President Joe Biden in 2022. At a November news conference, Powell indicated he would not step down if Trump asked him to resign.He has also said that the removal or demotion of top Fed officials was not permitted under the law.Trumps comments come with the backdrop of a legal case at the Supreme Court that could determine whether presidents can fire the heads of independent agencies such as the Fed. The case stems from Trumps firings of officials from two independent agencies. The Supreme Court last week let the firings stand while it considers the case. It could issue a broader ruling this summer that would enable the president to fire Fed officials, including the chair. Powell said the Fed is watching the case closely, adding that it might not apply to the Fed. Lawyers for the Trump administration have also argued that allowing the president to fire the two officials wouldnt erode the Feds independence. It is difficult to overstate the consequences at this stressed moment of a Court ruling that found that President Trump ... does have the authority to dismiss the heads of independent agencies and did not establish a clear carve-out for the Fed, Krishna Guha, an analyst at investment bank Evercore ISI, wrote on Thursday. If you liked the tariff debacle in markets, youd love the loss-of-Fed-independence trade.Powell started Trumps second term in a relatively secure spot with a low unemployment rate and inflation progressing closer to the Feds 2% target, conditions that could have spared the U.S. central banker from the presidents vitriol. But Trumps aggressive and haphazard tariffs have increased the threat of a recession with both higher inflationary pressures and slower growth, a tough spot for Powell, whose mandate is to stabilize prices and maximize employment. With the economy weakening because of Trumps choices, the president appears to be looking to pin the blame on Powell.Powell, in his remarks at the Economic Club of Chicago on Wednesday, said the Fed will base its decisions solely on what is best for all Americans.Thats the only thing were ever going to do, Powell said. Were never going to be influenced by any political pressure. People can say whatever they want. Thats fine, thats not a problem. But we will do what we do strictly without consideration of political or any other extraneous factors.Our independence is a matter of law, Powell continued. Were not removable except for cause. We serve very long terms, seemingly endless terms. Trump has unleashed a rash of tariffs that have put the U.S. economy and the Fed in an increasingly perilous spot. On April 2, the president rolled out aggressive tariff hikes based off U.S. trade deficits with other nations, causing a financial market backlash that almost immediately led him to announce a 90-day pause in which most countries would be charged a baseline 10% tariff while negotiations go forward. But Trump increased his tariff hikes on China to a rate of 145%, in addition to his existing tariffs on Canada, Mexico, autos and steel and aluminum.Wall Street banks such as Goldman Sachs have raised their odds that a recession could start. Consumers are increasingly pessimistic in surveys about their job prospects and fearful that inflation will shoot up as the cost of the import taxes get passed along to them. The risk of stagflation stagnant growth and high inflation would make it harder for the Fed to respond with the same playbook as recent downturns. The Budget Lab at Yale University estimated that the increased inflationary pressures from the tariffs would be equal to the loss of $4,900 in an average U.S. household.___AP journalists Sagar Meghani and Christopher Rugaber contributed reporting. AAMER MADHANI Madhani covers the White House for The Associated Press. He is based in Washington. twitter mailto JOSH BOAK Boak covers the White House and economic policy for The Associated Press. He joined the AP in 2013. twitter mailto

Nature, Published online: 17 April 2025; doi:10.1038/d41586-025-01198-6Study finds dozens of journals that have hiked their fees and started churning out papers after being acquired by small, recently formed companies.

Nature, Published online: 17 April 2025; doi:10.1038/d41586-025-01245-2Researchers who spoke to Nature say they dont have the money or staff to do fieldwork or process samples.

2K Games has signed a multi-year deal with a tournament platform provider for NBA 2K25 and upcoming iterations of the franchise.

American great Serena Williams said she would have been banned for 20 years and stripped of her Grand Slam titles had she failed drug tests like men's world No. 1 Jannik Sinner did last year.

by A.C. Thompson, ProPublica and FRONTLINE, and James Bandler, ProPublica ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as theyre published. A Wisconsin teenager accused of murdering two family members and plotting to assassinate President Donald Trump was inspired by Terrorgram, a white supremacist network that operated on the Telegram messaging and social media platform for half a decade, according to federal court records. The Terrorgram community, which has been linked to around three dozen criminal cases around the globe, including at least three mass shootings, was profiled last month in stories and a documentary produced by ProPublica and FRONTLINE.The court documents allege that Nikita Casap, a 17-year-old from Waukesha, Wisconsin, wrote a three-page manifesto calling for the assassination of Trump in order to foment a political revolution in the United States and save the white race from Jewish controlled politicians. In his manifesto, Casap allegedly encouraged people to read the writings of Juraj Krajk, a longtime Terrogram figure who murdered two people in an attack on an LGBTQ+ bar in Bratislava, Slovakia, in 2022, according to the court records. Casap also allegedly recommended two publications produced by the Terrorgram Collective, a secretive group that produced alleged hit lists, videos and written publications including instructions for building bombs and sabotaging critical infrastructure and distributed them throughout the Terrorgram ecosystem.Launched in 2019, Terrorgram was a constellation of scores of Telegram channels and chat groups focused on inciting acts of white supremacist terrorism and anti-government sabotage. At the networks peak, some Terrorgram channels drew thousands of followers. Over the past six months, however, the network has been disrupted as authorities in Canada, the U.S. and Europe have arrested key Terrorgram influencers and community members. But the violence hasnt stopped. Casap in February allegedly shot and killed his mother, Tatiana Casap, and stepfather, Donald Mayer; stole their property; and fled in their Volkswagen Atlas, Waukesha County prosecutors say. He was arrested in Kansas. Prosecutors have charged the teen with two counts of first-degree homicide, as well as identity theft and other theft charges. He is expected to be arraigned on May 7, according to court records. A witness told local investigators that Casap was in touch with a male in Russia through the Telegram app and they were planning to overthrow the U.S. government and assassinate President Trump, according to charging documents in the Wisconsin case. The newly unsealed federal court filings indicate that the FBI is investigating Casap in connection to the alleged assassination plot. The bureau declined to comment on the matter.Last fall, federal prosecutors accused two Americans of acting as leaders of the Terrorgram Collective and charged them with soliciting the murder of federal officials and a host of other terrorism-related offenses. The U.S. State Department has officially designated the Terrorgram Collective as a terrorist organization, as have officials in the United Kingdom and Australia. The two Americans have pleaded not guilty to the charges.Do absolutely anything you can that will lead to the collapse of America or any country you live in, Casap allegedly wrote in his manifesto, according to an FBI affidavit. This is the only way we can save the White race. The teens writings and online postings that are cited in the affidavit indicate that he is a believer in militant accelerationism, a concept that has become increasingly popular with neo-Nazis and other right-wing extremists over the past decade. Militant accelerationists aim to speed the collapse of modern society through acts of spectacular violence; from the ruins of todays democracies, they aim to build all-white ethno-states organized on fascist principles.Matthew Kriner, executive director of the Institute for Countering Digital Extremism, a nonprofit think tank, called the alleged Casap plot unique. Its the first time were explicitly seeing an individual tie an accelerationist act or plot with the president of the United States as a means of collapsing society, Kriner said. I think what we have here is a fairly clear-cut case of an individual who is being groomed to take drastic terrorist action in an accelerationist manner.Casaps public defender could not be reached for comment. A Telegram spokesperson said, Telegram supports the peaceful exchange of ideas; however, calls for violence are strictly prohibited by our Terms of Service and are removed proactively as well as in response to user reports."A ProPublica and FRONTLINE review shows that Casap was recently active in at least five extremist Telegram channels or chat groups, including a Russian-language neo-Nazi chat in which posters uploaded detailed instructions for crafting explosives, poisons and improvised firearms. He was also a member of a chat group with more than 4,300 participants run by the Misanthropic Division, a global neo-Nazi organization. Casap, according to the federal documents, also sought out information online about the Order of Nine Angles, a cult that blends Satanic concepts and Nazi ideology and has increasingly turned to Telegram to recruit and proselytize. This is a clear example of how Terrorgram continues to influence murder, said Jennefer Harper, a researcher who studies online extremism. Nikita was influenced online by an assortment of ideologies and groups that intersect with the Terrorgram ecosphere.

A man walks past Google's offices in London's Kings Cross area, on Aug. 10, 2024. (AP Photo/Brian Melley, File)2025-04-17T16:11:51Z Google has been branded an abusive monopolist by a federal judge for the second time in less than a year, this time for illegally exploiting some of its online marketing technology to boost the profits fueling an internet empire currently worth $1.8 trillion. The ruling issued Thursday by U.S. District Judge Leonie Brinkema in Virginia comes on the heels of a separate decision in August that concluded Googles namesake search engine has been illegally leveraging its dominance to stifle competition and innovation. After the U.S. Justice Department targeted Googles ubiquitous search engine during President Donald Trumps first administration, the same agency went after the companys lucrative digital advertising network in 2023 during President Joe Bidens ensuing administration in an attempt to undercut the power that Google has amassed since its inception in a Silicon Valley garage in 1998. Although antitrust regulators prevailed both times, the battle is likely to continue for several more years as Google tries to overturn the two monopoly decisions in appeals while forging ahead in the new and highly lucrative technological frontier of artificial intelligence. The next step in the latest case is a penalty phase that will likely begin late this year or early next year. The same so-called remedy hearings in the search monopoly case are scheduled to begin Monday in Washington D.C., where Justice Department lawyers will try to convince U.S. District Judge Amit Mehta to impose a sweeping punishment that includes a proposed requirement for Google to sell its Chrome web browser. MICHAEL LIEDTKE Liedtke has been covering technology and wide range of other business topics for The Associated Press since the turn of the century. twitter mailto

Utah's Grace McCallum completes on the floor exercise during the NCAA women's gymnastics championships, April 14, 2022, in Fort Worth, Texas. (AP Photo/Tony Gutierrez, file)2025-04-17T14:51:17Z WASHINGTON (AP) Thomas Bateman kept busy this year managing college fantasy teams in 12 different leagues, a lineup that included SECret Weapon and One and Dunne. Five of them won it all.These were not teams stocked with NFL or NBA players. All 12 were made up of college gymnasts, and the Chicago-based marriage and family therapist is just one member of a fervent and growing fan base that channels their love of the sport into fantasy leagues.Its such a great way to get to know the sport a bit, Bateman said. When I started off, I got these lists from College Gym News and picked athletes I didnt really know, so then I got to know teams I liked and then got familiar with athletes I want to draft. Its a great way to potentially grow the audience of the sport.Interest in gymnastics traditionally peaks with the Olympic cycle, but on the gymternet the online global community for devoted fans its a year-round sport. At the college level, major growth in name, image and likeness deals, viewership and streaming availability has been accompanied by a surge in fantasy leagues, too.This year, over 7,000 womens college gymnastics devotees have found their way to the Gymlytics and GymCastic fantasy platforms all within the last few years. From the Olympics to NCAA Gymlytics, which launched before the 2022 collegiate season, runs through the regular season and has a postseason bracket competition. GymCastic, in its second year, offers weekly fantasy matchups, including the NCAA postseason and elite meets later in the year. The two leagues take slightly different approaches. Gymlytics participants draft individual athletes for their team at the beginning of the season and set lineups for each week of competition. GymCastic runs a salary cap-style draft, in which athletes are valued at a certain number of gym rubles. Participants select athletes until their roster is filled while staying under the cap. Neither are the first platforms of their kind: Founders of both pointed to Kristen Watkins, a former college gymnast and self-taught programmer who created and ran College Fantasy Gymnastics for the decade leading into the pandemic-canceled 2020 season, as an inspiration. Watkins competed for the MIT gymnastics team until it was cut following the 2009 season, a period in which other college gymnastics programs were cut or coming under threat of reduction. The creation of the fantasy league, she said, was motivated in part because she wanted to see if there could be more interest in womens gymnastics. Subsequent leagues have hinged on the same idea.Thats the point of everything we do: Its very, very specific to the gymnastics fans, said Jessica OBeirne, creator of the popular GymCastic podcast and a co-founder of the fantasy league of the same name. We use the lingo of gymnastics. Its so niche and so specific.The Gymlytics audience is similarly a lot of diehard gymnastics fans, said Lauren Pickens, a co-creator. That includes former athletes. Pickens recalled hearing from recently graduated members of the championship-winning Michigan team who had barely missed the Gymlytics draft deadline but wanted to put teams together. (She helped them join in.) Growth beyond diehard fansLike all fantasy team managers who care about results, Bateman and other participants have their hands full. Week to week, participants set lineups across the four apparatuses vault, uneven bars, balance beam and floor exercise to maximize the total number of points their team scores. An injury or struggles at a weekend meet are factors in roster changes.Bateman joined Gymlytics in 2022 with friends who had been gymnasts at the University of Michigan. He named SECret Weapon after the Southeastern Conference, whose member school LSU is a repeat favorite at this weeks NCAA championships in Texas. One and Dunne bears the surname of LSU gymnast and popular influencer Olivia Dunne and the name worked in a league where each team could include just one athlete from each college.As GymCastic and Gymlytics have taken off, their creators have seen these diehard fans bring in friends and family who are less familiar with the sport. Weve gotten a lot of emails from people saying, my significant other did fantasy basketball or fantasy football and because theres a fantasy gymnastics, they wanted to connect with me and my passion so they joined a league, said GymCastic COO Steve Cooper. And now theyre screaming at the TV like I am.According to the Fantasy Sports & Gaming Association, the number of Americans over the age of 21 participating in fantasy sports grew by about 5% between 2017 and 2022. Its been much more robust for Gymlytics, which launched its first season with 1,000 teams and, according to co-founder Yarden Tamir, had nearly 7,000 teams across 55 countries this season; and for GymCastic, which has seen over 10% growth between its first and second seasons, per Cooper. While overall fantasy sports participation skews male by about a 2:1 ratio, according to FSGA data, the Gymlytics and GymCastic founders both estimated their participants were more gender balanced. Higher visibilityMultiple fantasy gymnastics participants and founders pointed to the 2021 and 2022 collegiate seasons as a turning point. Those seasons followed the delayed Tokyo Games and a 2021 Supreme Court decision allowing college athletes to earn endorsement money, marking the beginning of Olympics gymnasts being able to cash in and retain their NCAA eligibility. Other than Simone Biles, every member of that medal-winning Tokyo team, including alternates, went on to compete in the NCAA. Olympics is so fun but its hard to consistently follow elite athletes because oftentimes theyre only competing three or four times per year, Bateman said. NCAA gymnastics is fun, too, and its such an accessible format.Accessibility has also grown as streaming networks have jumped in. According to ESPN, the three most-watched gymnastics telecasts have been the three most recent national championships. In 2022, ESPN and affiliated platforms broadcast 40 meets across five platforms; after championships this year, it will be more than 60 meets across eight.FOX bought in this year. ESPN is doing GameDay-style shows to lead into their broadcast, said Brandis Heffner, the managing editor of College Gym News and a fantasy player. Giving that option to gymnastics fans has been a fantastic way to help build the sport.Running a custom fantasy league isnt without its challenges. League officials pointed to challenges with data availability and inconsistent information across conferences and regions, including judging details.Gymlytics and GymCastic have both gotten around it by leveraging the devotion among their participants, essentially crowdsourcing scores to get them into their databases. While there are improvements to be made on both the institutional and platform sides, the fantasy league founders all expressed optimism. There are a ton of little features we want to add and make the environment easier to use, more automated, Tamir said. If one actual person you dont know uses it, thats a huge win, but when thousands of users are using it on a daily basis, thats wild. Were just continuing to make that tent larger.___AP college sports: https://apnews.com/hub/college-sports MAYA SWEEDLER Sweedler is a reporter for The Associated Press, with a focus on analyzing election outcomes and procedures and explaining the intricacies of the electoral process. mailto

Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08710-yThe development of multimodal foundation models, pretrained on diverse omics datasets, to unravel the intricate complexities of molecular cell biology is envisioned.

Nature, Published online: 16 April 2025; doi:10.1038/d41586-025-00820-xHigh-resolution observations of ocean topography from the Surface Water and Ocean Topography (SWOT) mission reveal that small surface structures have a larger-than-expected impact on the oceans total energy budget.

Nationals reliever Jorge Lopez has been suspended three games for intentionally throwing at Pirates outfielder Andrew McCutchen.

Browns general manager Andrew Berry believes Travis Hunter is worth one of the top picks in the draft, even if he plays only one position, and compared him to Dodgers star Shohei Ohtani to describe his value.

Marine Corps combat veteran Matt Metzger poses for a portrait with a plate of mushrooms that he grows himself for microdosing psilocybin, Wednesday, March 26, 2025, in Olympia, Wash. (AP Photo/Lindsey Wasson)2025-04-17T13:17:19Z Microdosing is gaining popularity with a new breed of health seekers. These self-experimenters take a very small amount of psilocybin mushrooms or LSD to try to reduce anxiety, stress and depression. Some claim the practice gives them access to joy, creativity and connection they cant get otherwise.This isnt a full-blown acid trip or even close. If you see visions, its not a microdose. People who microdose dont do it every day. Instead, they take tiny doses intermittently, on a schedule or when they feel it could be beneficial.One small study suggests any psychological benefits come from users expectations the placebo effect. But the science is still new and research is ongoing.The substances are illegal in most places, but the wave of scientific research focused on the benefits of supervised hallucinatory experiences has spurred Oregon and Colorado to legalize psychedelic therapy. Further opening the door to microdosing, a handful of cities have officially directed police to make psychedelics a low priority for enforcement. This article is part of APs Be Well coverage, focusing on wellness, fitness, diet and mental health. Read more Be Well. What are people who microdose reporting?I started microdosing and within a couple of months, I had a general sense of well-being that I hadnt had in so long, said Marine Corps combat veteran Matt Metzger. He grows his own mushrooms in Olympia, Washington, where psilocybin has been decriminalized. Taking small amounts of psilocybin helps him cope with PTSD, he said.In Loveland, Colorado, Aubrie Gates said microdosing psilocybin has made her a better parent and enhanced her creativity. It makes you feel viscerally in your body a new way of being, a more healthy way of being, Gates said. And so instead of just like thinking with your conscious mind, Oh, I need to be more present, you feel what it feels like to be more present. What does the science say about microdosing?These kinds of claims are hard to measure in the lab, say scientists studying microdosing.For starters, belief is so important to the experience that empty capsules can produce the same effects.In one study involving people who microdose, participants didnt know until afterward whether they had spent four weeks taking their usual microdose or placebos. Psychological measures improved after four weeks for everyone in the study, regardless of whether they were taking microdoses or empty capsules.It appears that I was indeed taking placebos throughout the trial. Im quite astonished, wrote one of the study participants. It seems I was able to generate a powerful altered consciousness experience based only (on) the expectation around the possibility of a microdose.Scientists havent found lasting effects on creativity or cognition, according to a review of a handful of small placebo-controlled trials of microdosing LSD.One small study did find glimmers of an effect of small LSD doses on vigor and elation in people with mild depression when compared with a placebo.It may only work in some people and not in other people, so it makes it hard for us to measure it under laboratory conditions, said University of Chicago neuroscience researcher Harriet de Wit, who led the research. The potential has spurred an Australian company to conduct early trials of microdoses of LSD for severe depression and in cancer patients experiencing despair.Meanwhile, few rigorous studies of psilocybin microdosing have been done. Psilocybin mushrooms are the most often used among psychedelic drugs, according to a report by the nonpartisan Rand research group. Rand estimates that 8 million people in the U.S. used psilocybin in 2023 and half of them reported microdosing the last time they used it.A few words of caution about microdosingEven microdosing advocates caution that the long-term effects have not been studied in humans. Other warnings: Unregulated products from shady sources could contain harmful substances. And accidentally taking too much could cause disturbing sensations. The nonprofit Fireside Project offers free phone support for people during a psychedelic experience and has received hundreds of calls about microdosing.People may call just to simply process their experience, said project founder Josh White, who microdoses the plant iboga and LSD to continue to deepen the insight about my life that he gained in a full-blown psychedelic experience. Balazs Szigeti of University of California San Francisco, who has studied microdosing, said it may be a way to harness the placebo effect for personal benefit.Its like a self-fulfilling prophecy, Szigeti said. People who are interested in microdosing should give microdosing a try, but only if theyre enthusiastic about it, if they have a positive expectation about the benefits of microdosing.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institutes Science and Educational Media Group and the Robert Wood Johnson Foundation. The AP is solely responsible for all content. CARLA K. JOHNSON Johnson covers research in cancer, addiction and more for The Associated Press. She is a member of APs Health and Science team. twitter mailto

Florida State University students wait for news amid an active shooter incident at the schools campus in Tallahassee, Fla., Thursday, April 17, 2025 (AP Photo/Kate Payne)2025-04-17T16:26:44Z Lee esta historia en espaol TALLAHASSEE, Fla. (AP) A shooting Thursday on the Florida State University campus sent an unknown number of people to a nearby hospital, a medical center spokesperson said.Tallahassee Memorial Healthcare was receiving and treating people affected by the shooting, said Sarah Cannon, a hospital spokesperson. She said the hospital cannot yet confirm the number of people in care, and said the details are still unfolding.Ambulances, fire trucks and patrol vehicles from multiple law enforcement agencies raced toward the campus midday Thursday after the university issued an active shooter alert near the student union. Hundreds of students streamed away from the direction of the student union. Students were glued to their phones, some visibly emotional.Junior Joshua Sirmans, 20, was in the universitys main library when he said alarms began going off warning of an active shooter. Sirmans said law enforcement officers escorted him and other students out of the library with their hands over their heads.FBI officials are on scene, a spokesperson said.Students and faculty were instructed to seek shelter and await further instructions.Lock and stay away from all doors and windows and be prepared to take additional protective measures, the alert said. KATE PAYNE Payne writes about state government and education and is based in Tallahassee, FL. She is a Report for America corps member. twitter mailto

Nature, Published online: 17 April 2025; doi:10.1038/d41586-025-01265-yFreshwater insects used microplastic as a building material long before scientists coined the term.

Nature, Published online: 16 April 2025; doi:10.1038/d41586-025-01258-xScientists have captured a colossal squid in the deep sea for the first time. Plus, crows have surprising geometry skills and the world now has a plan in place for pandemics.

The Jets have signed Neal Pionk to a six-year, $42 million contract extension before the defenseman could hit free agency.

Future Hall of Fame quarterback Aaron Rodgers said Thursday on "The Pat McAfee Show" that he is not ready to make a decision on his plans for the 2025 season and allowed that retirement could still be a possibility.