Oxidation of retromer complex controls mitochondrial translation

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2025-03-26 21:16:09 -

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Nature, Published online: 26 March 2025; doi:10.1038/s41586-025-08756-ySystematic base-editing and computational screens identify specific cysteine residues on VPS35 in the retromer complex as key sensors that decrease mitochondrial translation in response to reactive oxygen species signals.

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