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A human-specific enhancer fine-tunes radial glia potency and corticogenesis
Nature, Published online: 14 May 2025; doi:10.1038/s41586-025-09002-1HARE5, a human accelerated region enhancer, modulates cortical development by influencing neural progenitor cell behaviour, leading to an enlarged neocortex with increased functional independence between cortical regions through amplified WNT signalling.
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