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A mechanical ratchet drives unilateral cytokinesis
Nature, Published online: 07 January 2026; doi:10.1038/s41586-025-09915-xDivision of embryonic cells with an incomplete contractile ring occurs by a ratchet mechanism with repeated cycles of cytoplasmic stiffening, which stabilizes the contractile actin band, and fluidization, which enables band ingression.
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