Oral 4-fluorouridine rescues nonhuman primates from advanced Lassa...

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2026-01-07 20:16:33 - Traduire -

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Oral 4-fluorouridine rescues nonhuman primates from advanced Lassa fever

Nature, Published online: 07 January 2026; doi:10.1038/s41586-025-09906-yTreatment with 4-fluorouridine (also known as EIDD-2749) in an African green monkey (Chlorocebus aethiops) model of Lassa disease resulted in complete clearance of infectious virus in a high proportion of cases and prolonged survival to the pre-determined study end-point in all cases.

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