<i>PPP2R1A</i> mutations portend...

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2025-07-02 17:20:04 -

WWW.NATURE.COM

<i>PPP2R1A</i> mutations portend improved survival after cancer immunotherapy

Nature, Published online: 02 July 2025; doi:10.1038/s41586-025-09203-8Inactivating PPP2R1A mutations correlate with better survival after immune checkpoint blockade in patients with ovarian clear cell carcinoma, suggesting that targeting the phosphatase 2A (PP2A) pathway may represent an effective startegy for improving responses to immunotherapy.

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