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WWW.LGBTQNATION.COMFDA approves twice-a-year HIV prevention drug that could help end the virus worldwideThe Food and Drug Administration (FDA) has approved Yeztugo (aka. lenacapavir or LEN), a twice-a-year injection that stops HIV from replicating inside cells, thereby reducing the risk of transmitting the virus to other people by 96%. HIV advocates hope it will help reduce national transmission rates because the medication is easier to take than the many current once-a-day medications.This is the single best opportunity in 44 years of HIV prevention, said Mitchell Warren, executive director of the AIDS Vaccine Advocacy Coalition (AVAC), an HIV advocacy nonprofit group, according to NBC News. The FDA approved the drug after Gilead Sciences, the drugs developer, found it to be overwhelmingly successful early into Phase 3 clinical trials last September. Related Now is a uniquely terrible time to cut funding for HIV New breakthrough drugs could eradicate AIDS. Why are we hobbling their distribution? The approval of LEN is a much-needed boost for HIV prevention, given the strength of the science and the simultaneous disruption in HIV programs globally, Warren added. But US FDA approval is just one in a series of steps needed to ensure that injectable LEN can help reduce the 1.3 million new HIV infections that occur each year. Never Miss a Beat Subscribe to our newsletter to stay ahead of the latest LGBTQ+ political news and insights. Subscribe to our Newsletter today Colleen Kelley, MD, one of the principal researchers in Phase 3 trials, said, Because adherence to oral products can be challenging for some people, twice-yearly injectable lenacapavir for PrEP has the potential to be one of the most impactful interventions we could have to drive down new infections and bring us closer to ending HIV in the United States.However, AVAC said it will take urgent and decisive action to ensure that the drug will reduce global HIV rates. Lenacapavirs current price as an HIV treatment is $3,450 per month, NBC News reported. AVAC has called on Gilead to provide the drug for $100 or below and to allow companies to develop generic forms of the drug. The group has also urged governments to quickly integrate the drug into their national health programs, and encouraged funders to join the Global Funds Childrens Investment Fund Foundation to provide at least enough of the drug to treat two million people globally through 2027. However, the drug arrives at a time when the current presidential administration has widely cancelled HIV research grants; slashed medical programs benefitting Black, Latino, and LGBTQ+ people most at-risk for contracting the virus; and also made severe reductions to the U.S. Agency for International Development (which oversaw HIV-prevention programs abroad).No one donor, national government, or manufacturer can realize this ambition alone, Warren said in a statement. All stakeholdersincluding Gilead, [the U.S. Presidents Emergency Plan for AIDS Relief], and the Gates Foundationmust act decisively to seize this opportunity, ensuring that all populationsregardless of geography, income, or identitybenefit from this innovative prevention option.This is the moment to build on the momentum of science, which has brought the field to this day, when LEN for PrEP is speeding through regulatory review faster than any prevention product to date, said Wawira Nyagah, AVACs director of product introduction & access. Translating this success into real impact on [global HIV reduction], led by communities around the world, must be a top priority among all stakeholders. In 2023, there were an estimated1.3 millionnew HIV infections worldwide,according to UNAIDS, a significant decrease from the peak of 3.3 million new infections in 1995.The availability of pre-exposure prophylactics (PrEP), a daily medication that can reduce the chance of transmission up to 99%, has been largely credited for the global reduction.Subscribe to theLGBTQ Nation newsletterand be the first to know about the latest headlines shaping LGBTQ+ communities worldwide.0 Comments 0 Shares 32 Views 0 Reviews
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WWW.NATURE.COMBioinspired capillary force-driven super-adhesive filterNature, Published online: 18 June 2025; doi:10.1038/s41586-025-09156-yStable coating of filters with a thin liquid layer enhances adhesion of airborne particulates while maintaining high air permeability, resulting in longer lifetimes and higher efficiency of these filters.0 Comments 0 Shares 30 Views 0 Reviews
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WWW.NATURE.COMA killswitch peptide solidifies protein droplets in living cellsNature, Published online: 18 June 2025; doi:10.1038/d41586-025-01875-6Human cells contain dozens of different types of proteinaceous droplets called biomolecular condensates. A newly developed tool provides insights into the behaviour of biomolecules in condensates and into the functions of condensates in living cells.0 Comments 0 Shares 31 Views 0 Reviews
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WWW.NATURE.COMFirst ever skull from Denisovan reveals what ancient people looked likeNature, Published online: 18 June 2025; doi:10.1038/d41586-025-01899-yAncient proteins and calcified dental plaque identify heavy-browed fossil from China as a Denisovan.0 Comments 0 Shares 34 Views 0 Reviews
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WWW.NATURE.COMStrategies for climate-resilient global wind and solar power systemsNature, Published online: 18 June 2025; doi:10.1038/s41586-025-09266-7Strategies for climate-resilient global wind and solar power systems0 Comments 0 Shares 33 Views 0 Reviews
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WWW.ESPN.COMBrowns rookie Sanders cited for driving 101 mphBrowns rookie quarterback Shedeur Sanders was cited by police early Tuesday morning for driving 101 mph in a 60 mph zone, according to police records.0 Comments 0 Shares 31 Views 0 Reviews
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WWW.ESPN.COMChants earn MCWS finals berth, win 26th straightCoastal Carolina advanced to the College World Series finals with a 11-3 victory over Louisville on Wednesday, scoring five of its six first-inning runs before making an out and extending its win streak to 26 games.0 Comments 0 Shares 31 Views 0 Reviews
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WWW.NYTIMES.COMTrump Travel Restrictions Bar Residents Needed at U.S. HospitalsLimits on travel and visa appointments have delayed or prevented foreign doctors from entering the country for jobs set to begin in weeks.0 Comments 0 Shares 31 Views 0 Reviews
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WWW.APARTMENTTHERAPY.COMThis Studio Kitchen Is So Tiny, It Only Took 8 Tiles to Transform the FloorThe after is so charming.READ MORE...0 Comments 0 Shares 29 Views 0 Reviews
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WWW.APARTMENTTHERAPY.COMWe Asked 3 Bartenders to Share the Best Bourbon for an Old-Fashioned, and They All Said the Same ThingTurns out, its all about the distillery.READ MORE...0 Comments 0 Shares 29 Views 0 Reviews
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WWW.ESPN.COMCFP meetings wrap with all formats still on tableCFP executive director Rich Clark said "pretty much everything's on the table" for potential formats for 2026 and beyond, but the group would like to make a decision by the fall.0 Comments 0 Shares 30 Views 0 Reviews
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WWW.NYTIMES.COMDemocrats Wary Response to Transgender Ruling Shows the Partys RetreatWhile some in the party denounced the Supreme Courts decision, other top leaders remained quiet, underscoring the partys discomfort on the issue.0 Comments 0 Shares 30 Views 0 Reviews
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WWW.NYTIMES.COMSocial Security Benefits Could Be Cut in 8 Years Unless Congress ActsThe nations key program for retiree benefits continues to see financing shortfalls. Unless Congress acts, those drops could lead to payment cuts in eight years.0 Comments 0 Shares 31 Views 0 Reviews
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WWW.NYTIMES.COMFor Food Network Fans, Anne Burrell Was the Fun-Loving AuntThe chef, who died Tuesday, built her stardom on a big, down-to-earth personality in which viewers could see themselves.0 Comments 0 Shares 33 Views 0 Reviews
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WWW.NYTIMES.COMU.S. Strike on Iran Would Bring Risks at Every TurnThe largest perils may lie in the aftermath, many experts say, just as they did in Afghanistan and Iraq.0 Comments 0 Shares 34 Views 0 Reviews
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WWW.NYTIMES.COMThe Supreme Court Upheld a State Ban on Transgender Care for MinorsAlso, Trumps cryptic Iran comments fueled fears of a wider war. Heres the latest at the end of Wednesday.0 Comments 0 Shares 30 Views 0 Reviews
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WWW.APARTMENTTHERAPY.COMThis Dollar Tree Decor Hack Looks 4x More Expensive Than It CostsNot a DIYer? You can buy it premade, too.READ MORE...0 Comments 0 Shares 32 Views 0 Reviews
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WWW.NYTIMES.COMHurricane Erick Nears Mexicos Coast as Category 3 StormIf you are in low-lying areas, near rivers, near waterways, it is best for you to go to shelters, President Claudia Sheinbaum said.0 Comments 0 Shares 33 Views 0 Reviews
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WWW.NYTIMES.COMTrump, Iran and the Specter of Iraq: We Bought All the Happy TalkAs President Trump ponders swift military action in Iran, there were similar expectations that the war in Iraq would be quick and triumphant.0 Comments 0 Shares 32 Views 0 Reviews
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For Tennessees Transgender Families, Supreme Court Ruling Was Bitter, but ExpectedThe state has been a leader in the rollback of L.G.B.T.Q. rights.0 Comments 0 Shares 30 Views 0 Reviews
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WWW.NYTIMES.COMThe Supreme Court Case on Trans Care Ruled Against My DaughterAs parents, we know better than state officials what our child needs.0 Comments 0 Shares 32 Views 0 Reviews
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WWW.NYTIMES.COMHundreds of Iranian Civilians Die in Israeli Strikes, Including a Poet and an EquestrianIsrael has said it does not target Iranian civilians, but hundreds have died in the violence, among them a poet and her family, an equestrian and a graphic designer.0 Comments 0 Shares 30 Views 0 Reviews
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WWW.ESPN.COMTransfer rumors, news: Newcastle eye move for RashfordNewcastle are reportedly looking at signing Manchester United's Marcus Rashford. Transfer Talk has the latest news, gossip and rumors.0 Comments 0 Shares 31 Views 0 Reviews
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WWW.NYTIMES.COMKaren Read Acquitted of Murder and Manslaughter in Retrial: What We KnowA jury found Ms. Read not guilty of murder and manslaughter on Wednesday in the death of her boyfriend, a Boston police officer, in 2022. Her first trial last year ended in a mistrial.0 Comments 0 Shares 29 Views 0 Reviews
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WWW.NYTIMES.COMNew Owner for High Times Magazine Bets on a Counterculture ComebackThe anti-establishment magazine, which was taken over by a private equity firm in 2017, was purchased this week by an avid fan and reader for $3.5 million.0 Comments 0 Shares 30 Views 0 Reviews
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Stanley Nelson, Journalist Who Investigated Klan Murders, Dies at 69Born and raised in Louisiana, he investigated unresolved civil-rights-era killings in the Deep South. His reporting on one of those cases made him a Pulitzer Prize finalist.0 Comments 0 Shares 33 Views 0 Reviews
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WWW.NYTIMES.COMWilliam G. Young, a Reagan-Appointed Judge, Is Fast-Tracking Trump to TrialJudge William G. Youngs long career has been punctuated by high-profile cases and outspoken advocacy for the judiciarys value and fact-finding power.0 Comments 0 Shares 29 Views 0 Reviews
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WWW.NYTIMES.COMU.S. to Review Social Media Posts of Student and Scholar Visa ApplicantsThe State Department is restarting the processing of visa applications from students and visiting scholars, but is screening for hostility toward the United States.0 Comments 0 Shares 32 Views 0 Reviews
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WWW.NYTIMES.COMEx-Yankee Is Awarded About $500,000 in Damages for Moldy Greenwich MansionJosh Donaldson, a former American League Most Valuable Player with Toronto, sued his former landlord over the conditions at his $55,000-a-month rental property.0 Comments 0 Shares 31 Views 0 Reviews
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WWW.ESPN.COMLSU plates three runs in 9th to make MCWS finalsDown to its last out, LSU capitalized on a two-run miscue by Arkansas in the ninth inning before posting a walk-off victory over Arkansas to advance to the Men's College World Series finals.0 Comments 0 Shares 33 Views 0 Reviews
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WWW.ESPN.COMAlba returning, Messi fit as Miami faces PortoInter Miami CF head coach Javier Mascherano said Jordi Alba and Lionel Messi will both be available for selection tomorrow in the team's second Club World Cup group stage match against FC Porto at Mercedes-Benz Stadium in Atlanta.0 Comments 0 Shares 30 Views 0 Reviews
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WWW.ESPN.COMXabi says Madrid makeover 'a process' after drawXabi Alonso called for patience after Real Madrid's 1-1 draw with Al Hilal in their opening game at the Club World Cup, saying implementing the changes he wants to make "will take time."0 Comments 0 Shares 31 Views 0 Reviews
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WWW.ESPN.COMJuventus net five in commanding CWC openerRandal Kolo Muani and Francisco Conceio both scored twice, leading Juventus to a dominant 5-0 victory over Al Ain in their Club World Cup debut in Washington, D.C. on Wednesday night.0 Comments 0 Shares 32 Views 0 Reviews
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WWW.ESPN.COMPoch: USMNT not playing to get revenge on criticsUSMNT coach Mauricio Pochettino said he's not seeking vengeance against his critics after a positive start for the men's national team in the 2025 Gold Cup.0 Comments 0 Shares 26 Views 0 Reviews
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WWW.ESPN.COMLSU plates three runs in 9th, makes MCWS finalsDown to its last out, LSU capitalized on a two-run miscue by Arkansas in the ninth inning before posting a walk-off victory to advance to the Men's College World Series finals.0 Comments 0 Shares 31 Views 0 Reviews
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WWW.NYTIMES.COMUnder Chinas Threat, Taiwan Needs Its Own Power Sources More Than EverTaiwan, which makes most of the worlds advanced computer chips, relies almost entirely on imported energy.0 Comments 0 Shares 32 Views 0 Reviews
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WWW.NYTIMES.COMYour A.I. Queries Come With a Climate CostWhen it comes to artificial intelligence, more intensive computing uses more energy, producing more greenhouse gases.0 Comments 0 Shares 29 Views 0 Reviews
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WWW.ESPN.COMYanks finally score, otherwise sputter in latest lossThe Yankees scored their first runs after 30 straight scoreless innings, but still fell 3-2 to the Angels on Wednesday night for their sixth consecutive loss.0 Comments 0 Shares 31 Views 0 Reviews
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WWW.ESPN.COMRays' 8-run comeback largest in MLB this seasonThe Rays overcame an eight-run deficit to beat the Orioles 12-8 on Wednesday night in the largest comeback in the majors this season, which also matched Tampa Bay's biggest comeback in franchise history.0 Comments 0 Shares 31 Views 0 Reviews
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WWW.ESPN.COMSources: Draft prospect Bailey cancels 76ers visitFormer Rutgers star Ace Bailey has canceled a visit to the Philadelphia 76ers, sources told ESPN, and has yet to visit any NBA teams ahead of next week's NBA draft.0 Comments 0 Shares 31 Views 0 Reviews
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A Progressive Future Depends on National IdentityTough border policies arent just good politics. Theyre progressive, as Britains Labour Party shows.0 Comments 0 Shares 30 Views 0 Reviews
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WWW.NYTIMES.COMAn Iran Strategy for TrumpFirst, destroy Fordo. Then make the mullahs an offer they cant refuse.0 Comments 0 Shares 30 Views 0 Reviews
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WWW.NYTIMES.COMHurricane Erick Nears Mexico as a Category 4 StormErick set off flash floods in the states of Oaxaca and Guerrero. A stretch of the Pacific coastline, including Acapulco, was under a hurricane warning.0 Comments 0 Shares 33 Views 0 Reviews
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SpaceX Starship Explodes During Test in TexasThe Starship experienced a major anomaly before starting its 10th flight test. Elon Musks giant moon and Mars rocket has a mixed record of success.0 Comments 0 Shares 33 Views 0 Reviews
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WWW.NATURE.COMRevealed: How the brain turns stress into a bad night's sleepNature, Published online: 19 June 2025; doi:10.1038/d41586-025-01910-6Neurons deep in the brain influence how stressful experiences disrupt both sleep and memory.0 Comments 0 Shares 31 Views 0 Reviews
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WWW.NYTIMES.COMThe Progressive Regulator With Trumpist FansLina Khan wants to overthrow the autocrats of trade.0 Comments 0 Shares 30 Views 0 Reviews
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WWW.NYTIMES.COMAmerica Cant Bomb Iran Out of Making a Nuclear WeaponTrump should judge the efficacy of any military action in Iran by the same standards against which he previously assessed diplomacy.0 Comments 0 Shares 33 Views 0 Reviews
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WWW.UNCLOSETEDMEDIA.COMWhy a Nonprofit Model is the Future of LGBTQ JournalismSubscribe nowWhen I decided to move forward with Uncloseted Media in 2024, it took me about two minutes to realize that the only way an investigative LGBTQ-focused news publication can succeed and stay afloat in today's media ecosystem is through a nonprofit model.Producing rigorous journalism takes time and will pretty much *never* turn a profit. Journalismlike any other piece of mediarelies on clicks and engagement. If I have an intern whip up a list of the 10 hottest gay influencers in New York City or design an Instagram slide announcing that the most famous Gen Z content creator has come out as bisexual, that will most likely go viral. And that takes between 5 and 30 minutes to create.On the other hand, if we produce a 2,000-word wonky policy piece about the spinoff effects of Trumps billions of dollars in cuts to HIV programswhich, as youll see below, were publishing on Tuesdayit is a harder sell.Could it go viral? Sure! But its not as sexy or as sticky or as bite-sized as a fun TikTok you *must* share with your friends. Whats more, doing the HIV piece well requires our highly skilled team of journalists to spend a very long time ideating, writing, reporting, investigating and fact-checking. It also requires a highly skilled editor to get the story into strong enough shape for mass publication. In addition, it might need to be reviewed by a legal and standards team to avoid getting sued.So to make money in media, its a basic formula:MINIMAL TIME TO PRODUCE + MAXIMUM LIKELIHOOD OF ENGAGEMENT AND CLICKS = PROFIT!So, if all I cared about was money, Id say give me the bisexual content creators coming out announcement on Instagram ALL.DAY.LONG.The days of for-profit newspapers are gone. But the need for investigative journalism in the U.S. is more critical than ever. To achieve this, I believe well see more nonprofit newsrooms emerge and the model of philanthropy-supported journalism will grow exponentially over the next few years.If we dont see that growth, news deserts will expand and corruption, bad actors and systems of injustice will go unchecked and will operate in a deeper shade of darkness. Subscribe for LGBTQ-focused, accountability journalism.I was in Washington, DC on Tuesday to accept our Trade Journalism Award from the National Institute for Health Care Management Foundation. Huge congrats to Anastassia Gliadkovskaya of Fierce Healthcare and our very own Sam Donndelinger for their powerful reporting on PrEP deserts in the Bible Belt and how those who need HIV-prevention the mostlow-income LGBTQ people of colorhave the most trouble accessing it.Subscribe nowSupreme Court upholds state ban on transgender minors using puberty blockers, hormone therapy (USA Today)In her dissent, Justice Sotomayor said the Supreme Court abandons transgender children and their families to political whims."Suspect in Minnesota Shooting Linked to Security Company, Evangelical Ministry (Wired)The alleged shooter is a 57-year-old white male; according to his ministry's website, he sought out militant Islamists in order to share the gospel and tell them that violence wasn't the answer.Judge deems Trump's cuts to National Institutes of Health illegal (NBC News)The federal judge said the NIH violated federal law by arbitrarily canceling more than $1 billion in research grants because of their perceived connection to DEI initiatives.Childrens Hospital Los Angeles halts transgender care under pressure from Trump (LA Times)Families and survivors have waited 9 years for a memorial for Pulse shooting victims in Orlando. Now the city is moving forward with plans (CNN)Now, as the city marks the nine-year anniversary of the tragedy at Pulse on June 12, city leaders and local activists say they have renewed hope that construction of a permanent memorial site will begin next June.Over the next week, be on the lookout for new Uncloseted reporting: Shannon Burns grew up in a conservative Christian environment outside of Toronto, where homosexuality was seen as a sin and where women were expected to be subordinate to men. Through her teens, she kept two secrets: her lesbian identity and the fact that her stepfather was molesting her every night in her bedroom. Years later, Shannon has left the church and is speaking out about her experience as a child sexual assault survivor to raise awareness about the alarming intersection between religion, LGBTQ identity, gender roles and sexual assault. I interview her for our third episode of Beneath the Grid. The Trump administration has been cutting billions of dollars from funding for HIV care, prevention, and research at home and abroad. Hope Pisoni investigates the devastating impact these cuts are already having on the people living with the virus, those susceptible to contracting it, and the research and technology surrounding a vaccine that could end HIV globally.Thanks for reading! Feel free to email me with questions, complaints and story ideas! Spencer Macnaughton, Editor-In-Chief spencer@unclosetedmedia.comIf objective, nonpartisan, rigorous, LGBTQ-focused journalism is important to you, please consider making a tax-deductible donation through our fiscal sponsor, Resource Impact, by clicking this button:Donate to Uncloseted Media0 Comments 0 Shares 31 Views 0 Reviews
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WWW.NYTIMES.COMIran Has Its Back Against the WallThe Iranian regime finds itself in its most difficult position 46 years after the revolution that brought it to power. But does it mean the end?0 Comments 0 Shares 30 Views 0 Reviews