Sleep pressure accumulates in a voltage-gated lipid peroxidation...

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2025-03-19 18:16:02 -

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Sleep pressure accumulates in a voltage-gated lipid peroxidation memory

Nature, Published online: 19 March 2025; doi:10.1038/s41586-025-08734-4Sleep-inducing neurons in Drosophila rely on Hyperkinetic, the -subunit of the KV1 channel Shaker, to monitor sleep need by translating lipid peroxidation events into changes in the oxidation state of a stably bound NADPH cofactor.

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