STING agonist-based ER-targeting molecules boost antigen...

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STING agonist-based ER-targeting molecules boost antigen cross-presentation

Nature, Published online: 26 March 2025; doi:10.1038/s41586-025-08758-wSTING agonist-based endoplasmic reticulum-targeting molecules can be conjugated directly onto antigens to deliver them to the cross-presentation pathway, improving CD8+ T cell responses against tumours and viruses.

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