Plasticity of the mammalian integrated stress response

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2025-03-28 04:16:42 - ترجمة -

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Nature, Published online: 26 March 2025; doi:10.1038/s41586-025-08794-6A study describes the split integrated stress response, a cellular stress response mechanism characterized by reduced eIF2B activity without eIF2 phosphorylation, which activates the eIF4EATF4PCK2 axis, enabling metabolic reprogramming.

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