DNA-guided transcription factor interactions extend human gene...

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2025-04-11 08:17:03 - ترجمة -

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DNA-guided transcription factor interactions extend human gene regulatory code

Nature, Published online: 09 April 2025; doi:10.1038/s41586-025-08844-zA large-scale analysis of DNA-bound transcription factors (TFs) shows how the presence of DNA markedly affects the landscape of TF interactions, and identifies composite motifs that are recognized by complexes of TFs rather than by individual ones.

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