Perturbing LSD1 and WNT rewires transcription to synergistically...

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2025-04-17 21:16:18 - Traduire -

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Perturbing LSD1 and WNT rewires transcription to synergistically induce AML differentiation

Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08915-1Simultaneous inhibition of LSD1 and GSK3 kinase promotes cell differentiation, providing a therapeutic strategy for treating acute myeloid leukaemia.

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