Activation of lysosomal iron triggers ferroptosis in cancer

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2025-05-07 22:16:42 - Traduire -

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Nature, Published online: 07 May 2025; doi:10.1038/s41586-025-08974-4Some cancer cells exhibit high loads of reactive iron in lysosomes, and this feature is exploited by using fentomycin-1, a newly developed small molecule, to induce ferroptosis.

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