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Oncogenic fusions converge on shared mechanisms in initiating astroblastoma
Nature, Published online: 14 May 2025; doi:10.1038/s41586-025-08981-5The molecular mechanisms of astroblastoma development are identified, whereby distinct gene fusions upregulate shared transcriptional networks to disrupt the normal development of ventral telencephalon neural progenitors, which leads to oncogenesis.
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