Targeting symbionts by apolipoprotein L proteins modulates gut...

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2025-05-19 13:16:17 - ترجمة -

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Targeting symbionts by apolipoprotein L proteins modulates gut immunity

Nature, Published online: 14 May 2025; doi:10.1038/s41586-025-08990-4APOL9a/b proteins coat mouse intestinal bacteria with high specificity, and genetic abolition of ceramide-1-phosphate synthesis pathways in the symbiote Bacteroides thetaiotaomicron significantly decreases this binding of APOL9a/b to the bacterium.

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