Immune control of metastatic cancer at the edge of the central...

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2025-05-19 17:16:50 -

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Immune control of metastatic cancer at the edge of the central nervous system

Nature, Published online: 14 May 2025; doi:10.1038/d41586-025-01470-9Leptomeningeal metastasis is a deadly consequence of cancer that creates an unusually inflamed environment around the brain and spinal cord. One of the inflammatory signalling molecules found in cerebrospinal fluid, interferon-, induces an antitumour immune response through an unexpected series of cellcell interactions.

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