Gene-drive-capable mosquitoes suppress patient-derived malaria in...

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Gene-drive-capable mosquitoes suppress patient-derived malaria in Tanzania

Nature, Published online: 10 December 2025; doi:10.1038/s41586-025-09685-6Engineering of local Anopheles gambiae under containment enables the generation of a transgenic strain equipped with non-autonomous gene drive capabilities that robustly inhibits genetically diverse Plasmodium falciparum isolates obtained from naturally infected children.

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