Uncovering the role of LINE-1 in the evolution of lung adenocarcinoma

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2025-12-10 22:16:45 - Translate -

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Nature, Published online: 10 December 2025; doi:10.1038/s41586-025-09825-yLung adenocarcinomas bearing the ID2 mutational signature display increased LINE-1 retrotransposon activity, which contributes to their fast evolutionary dynamics and aggressive phenotype.

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