Programmable protein ligation on cell surfaces

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2025-07-30 19:25:02 -

WWW.NATURE.COM

Nature, Published online: 30 July 2025; doi:10.1038/s41586-025-09287-2A synthetic biology system called SMART has been developed that uses conditional protein splicing for the programmable ligation of functional proteins from previously defined molecular combinations on cell surfaces.

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