ACLY inhibition promotes tumour immunity and suppresses liver cancer

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2025-07-30 21:20:24 -

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ACLY inhibition promotes tumour immunity and suppresses liver cancer

Nature, Published online: 30 July 2025; doi:10.1038/s41586-025-09297-0Using metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma mouse models, an ATP citrate lyase inhibitor reduces tumour burden and enhances efficacy of current standards of care.

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