Microglia regulate GABAergic neurogenesis in prenatal human brain...

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2025-08-06 21:20:41 -

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Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1

Nature, Published online: 06 August 2025; doi:10.1038/s41586-025-09362-8Microglia-derived IGF1 promotes the proliferation of GABAergic progenitors and neuroblasts in the human medial ganglionic eminence, contributing to the extended production of GABAergic neurons and an expanded cognitive capacity in the human brain.

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