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Robust partitioning of cell contents by physical instabilities and biological clocks
Nature, Published online: 11 February 2026; doi:10.1038/d41586-026-00021-0In early embryos, the first cell divisions must be extremely rapid and precisely controlled to ensure successful development. This balance is found to arise from a tight coupling between the clock that drives the cell-division cycle and a physical instability in the cell skeleton. This coupling robustly partitions cell contents and drives development.
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