Crystal structures of agonist-bound human cannabinoid receptor...

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2025-08-27 19:34:28 -

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Crystal structures of agonist-bound human cannabinoid receptor CB<sub>1</sub>

Nature, Published online: 27 August 2025; doi:10.1038/s41586-025-09454-5Crystal structures of human CB1 bound to two cannabinoid agonists reveal key features, including a twin toggle switch and binding pocket reduction, advancing understanding of receptor dynamics and guiding cannabinoid drug design.

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