Maternal stress triggers early-life eczema through fetal mast cell...

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2025-08-27 19:34:31 -

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Maternal stress triggers early-life eczema through fetal mast cell programming

Nature, Published online: 27 August 2025; doi:10.1038/s41586-025-09419-8Prenatal stress triggers molecular dysregulations in fetal neuroimmune circuits, leading to altered mast cell and sensory neuron function, which predisposes offspring to develop eczema in response to otherwise harmless mechanical friction after birth.

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