DNA2 enables growth by restricting recombination-restarted replication

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2025-09-03 16:35:06 -

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Nature, Published online: 03 September 2025; doi:10.1038/s41586-025-09470-5DNA2 suppresses recombination-restarted replication and checkpoint activation at stalled forks, and its loss triggers recombination-dependent synthesis, checkpoint signalling and cell-cycle exit, highlighting its essential role in proliferation and growth failure in primordial dwarfism.

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