Dynamic fibroblastimmune interactions shape recovery after brain...

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2025-09-03 17:37:07 -

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Dynamic fibroblastimmune interactions shape recovery after brain injury

Nature, Published online: 03 September 2025; doi:10.1038/s41586-025-09449-2Spatial transcriptomic studies and lineage tracing reveal that, after brain injury, transient profibrotic fibroblasts develop from existing brain fibroblasts, infiltrate lesions, regulate the local immune response and lead to beneficial scar tissue formation.

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