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2025-09-12 21:41:35 -

WWW.NATURE.COM

Loss-of-function mutations in <i>PLD4</i> lead to systemic lupus erythematosus

Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09513-xPLD4 loss-of-function mutations in patients with systemic lupus erythematosus leads to excessive activation of TLR7 and TLR9.

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