Structures of Marburgvirus glycoprotein and its complex with NPC1...

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2026-03-11 18:16:09 - Übersetzen -

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Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10240-0Marburgvirus glycoprotein binds to the endosomal receptor NPC1 in a distinct orientation with higher affinity compared with Ebola virus glycoprotein, accompanied by fusion-relevant rearrangements, enabling more efficient viral entry.

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