Facile induction of immune tolerance by an interleukin-2TGF...

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2026-03-11 21:16:31 - ترجمة -

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Facile induction of immune tolerance by an interleukin-2TGF surrogate agonist

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10208-0A fusion protein designed to comprise IL-2 and a helminth-derived TGF mimic activates IL-2 and TGF signalling pathways in IL-2 receptor-expressing T cells and induces stable antigen-specific regulatory T cells in peripheral lymphoid organs.

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