Snapshots of the dynamic basis of NTSR1 G protein subtype promiscuity

A distribuit un link

2026-03-11 21:16:33 - Translate -

WWW.NATURE.COM

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10120-7Time-resolved cryo-electron microscopy during activation of Gi1 and G11 heterotrimers bound to NTSR1 enables isolation of multiple transient complexes along the activation pathway and reveals structural motifs that stabilize these intermediates.

0 Commentarii 0 Distribuiri 32 Views 0 previzualizare