Tumour promotion through the lens of evolution

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2026-04-15 15:48:45 - Translate -

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Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10386-xThis Review revisits tumour initiation and promotion in light of clonal diversity and the presence of cancer driver mutations in normal tissues, aiming to understand mechanisms that enable environmental and endogenous factors to expand tumorigenic clones.

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