Mapping convergent regulators of melanoma drug resistance by...

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2026-04-15 16:03:33 - Traduzir -

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Mapping convergent regulators of melanoma drug resistance by PerturbFate

Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10367-0PerturbFate is a high-throughput, cost-effective, single-cell platform that systematically profiles CRISPR interference perturbations to reveal common regulatory nodes and convergent phenotypic states across diverse genetic alterations linked to vemurafenib resistance in melanoma cells.

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