Molecular basis for methylation-sensitive editing by Cas9

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2026-04-15 16:36:48 - Übersetzen -

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Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10384-zThermoCas9, a genome-editing enzyme that is sensitive to the DNA methylation status of the target locus, is characterized and shows promise for targeting hypomethylated DNA regions in cancer cells.

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