Template-driven scaffolding of...

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2026-04-15 16:36:53 - ترجمة -

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Template-driven scaffolding of SCF<sup>FBXO42</sup> regulates PP2A degradation

Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10368-zThe E3 ligase SCFFBXO42 degrades holoenzyme-free PP2Ac in complex with the coiled-coil protein CCDC6 to maintain cancer cell fitness

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