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This is a locator map for Yemen with its capital, Sanaa. (AP Photo)2025-12-03T15:13:48Z DUBAI, United Arab Emirates (AP) Yemens Houthi rebels on Wednesday released mariners held since a July attack on the ship Eternity C in the Red Sea, an assault that killed at least four on board and sank the vessel.The Iranian-backed Houthis, who have been targeting ships during the Israel-Hamas war, said via their al-Masirah satellite news channel that Oman had taken custody of the mariners, who were flying to the sultanate.Oman did not immediately acknowledge the release. However, a Royal Oman Air Force jet landed earlier Wednesday in Sanaa, the Yemeni capital held for over a decade by the rebels, according to flight-tracking data analyzed by The Associated Press. Following the Houthi announcement, the plane was tracked leaving Yemeni airspace.The Philippines on Tuesday said it expected nine Filipino mariners held by the Houthis since the attack to be released. The Foreign Ministry in Manila described the mariners as being held hostage by the Houthis since the attack. The Houthis offered no immediate breakdown on the nationalities of those released. It had described their forces as rescuing the men after they abandoned the crippled ship following the attack. Al-Masirah on Wednesday published an image of six of the men, without expressions, wearing the black-and-white checkered keffiyeh scarf often associated with the Palestinians. The attack on the Liberian-flagged bulk carrier also left 11 people missing. The Houthis have targeted more than 100 ships with missiles and drones in their campaign, sinking four vessels. The attacks have killed at least nine mariners, after a crew member aboard one vessel targeted, the Minervagracht, died of his wounds in October. The Houthis have held mariners for months in the past, and it wasnt immediately clear why they released the mariners now. The Houthis stopped their attacks during a brief, earlier ceasefire in the war in Gaza. They later became the target of a weekslong campaign of airstrikes ordered by U.S. President Donald Trump before he declared a ceasefire had been reached with the rebels. The current ceasefire in the war has again seen the Houthis hold their fire. Meanwhile, the future of talks between the U.S. and Iran over Tehrans battered nuclear program is in question after Israel launched a 12-day war against the Islamic Republic in June that saw the U.S. bomb three Iranian atomic sites.___Associated Press writer Jim Gomez in Manila, Philippines, contributed to this report. JON GAMBRELL Gambrell is the news director for the Gulf and Iran for The Associated Press. He has reported from each of the Gulf Cooperation Council countries, Iran and other locations across the world since joining the AP in 2006. twitter instagram mailto

Actor Matthew Perry participates in the BUILD Speaker Series to discuss the mini-series "The Kennedys After Camelot" in New York, March 30, 2017. (Photo by Evan Agostini/Invision/AP, File)2025-12-03T05:00:46Z LOS ANGELES (AP) A doctor who pleaded guilty to selling ketamine to Matthew Perry in the weeks before the Friends stars overdose death is set to be the first of five people sentenced in the case on Wednesday. Perrys family and possibly others affected by his death will have a chance to make a statement in federal court in Los Angeles before the sentencing of Dr. Salvador Plasencia. Prosecutors are asking U.S. District Judge Sherilyn Peace Garnett to sentence Plasencia, 44, to three years in prison after a plea agreement where the doctor admitted to illegally selling Perry large amounts of ketamine. He was not accused of selling the actor the dose that investigators say killed him on Oct. 28, 2023. Perry had been taking the surgical anesthetic ketamine legally as a treatment for depression. But when his regular doctor wouldnt provide it in the amounts he wanted, he turned to Plasencia, who admitted to illegally selling to Perry despite knowing he was a struggling addict. He texted another doctor that Perry was a moron who could be exploited for money, according to court filings. Rather than do what was best for Mr. Perry someone who had struggled with addiction for most of his life defendant sought to exploit Perrys medical vulnerability for profit, the prosecutions sentencing memo said. Plasencias lawyers tried to give a sympathetic portrait of him in their memo, as a man who rose out of poverty to become a doctor beloved by his patients, some of whom provided testimonials about him for the court. The attorneys called his selling to Perry reckless and the biggest mistake of his life.Remorse cannot begin to capture the pain, regret and shame that Mr. Plasencia feels for the tragedy that unfolded and that he failed to prevent, the memo said.But, the lawyers wrote, a sentence of imprisonment is neither necessary nor warranted. He has already lost his medical license, his clinic, and his career. He has also been viciously attacked in the media and threatened by strangers to the point where his family has moved out of state for their safety. Plasencias lawyers said he has moved to Arizona with his wife and 2-year-old son, for whom he is a loving caretaker.I want him to be proud of his father, Plasencia said in a video he and his lawyers made for the judge. I made mistakes, but I want him to know that I tried to make better choices after my mistakes.Plasencia pleaded guilty in July to four counts of distribution of ketamine. Prosecutors agreed to drop five different counts. The agreement came with no sentencing guarantees, and legally Garnett can give him up to 40 years.Perrys mother Suzanne Perry and his stepfather, Dateline journalist Keith Morrison, have attended previous hearings. They could be among those given a chance to speak before Plasencia is sentenced.The other four defendants who reached deals to plead guilty will be sentenced at their own hearings in the coming months. Perry struggled with addiction for years, dating back to his time on Friends, when he became one of the biggest stars of his generation as Chandler Bing. He starred alongside Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matt LeBlanc and David Schwimmer for 10 seasons from 1994 to 2004 on NBCs megahit. ANDREW DALTON Dalton covers entertainment for The Associated Press, with an emphasis on crime, courts and obituaries. He has worked for the AP for 20 years and is based in Los Angeles. mailto

Nature, Published online: 03 December 2025; doi:10.1038/d41586-025-03969-7Her experiments on the heaviest elements deepened our understanding of radioactivity.

Nature, Published online: 03 December 2025; doi:10.1038/d41586-025-03925-5Urban health and well-being is central to the worlds future prospects

Nature, Published online: 03 December 2025; doi:10.1038/d41586-025-03926-4Cutting-edge materials and thoughtful urban planning can help cities beat the negative heating effects of climate change.

Nature, Published online: 03 December 2025; doi:10.1038/d41586-025-03929-1Landscape architect and neuroscientist Agnieszka Olszewska-Guizzo explains how she measures and optimizes the mental-health benefits of urban spaces.

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A protestor waves a flag in a pouring rain during a demonstration against an impending Customs and Border Patrol immigration crackdown in New Orleans, Monday, Dec. 1, 2025. (AP Photo/Gerald Herbert)2025-12-03T13:47:28Z NEW ORLEANS (AP) A federal immigration crackdown began Wednesday in New Orleans under an operation that a Homeland Security official said would target violent criminals, expanding the Trump administrations sweeps that have unfolded in other U.S. cities. The aim of the operation is to capture immigrants who were released after their arrests for crimes such as home invasion, armed robbery and rape, Homeland Security Department Assistant Secretary Tricia McLaughlin said in a statement.Immigration officials have blanketed big cities and small towns across the nation since January while carrying out Republican President Donald Trump s aggressive mass deportation efforts. Federal agents have launched high-profile immigration crackdowns in cities including Chicago and Charlotte, North Carolina. Another operation is expected in the coming days in Minnesota, targeting Somali immigrants. The enforcement tactics have been met with protests and lawsuits challenging the aggressive force and how the arrests are being carried out.Its not clear how many agents are being deployed for the operation in New Orleans a one-of-a-kind American city known as the birthplace of jazz and for its Mardi Gras celebrations and rich blend of French, Spanish, African and Native American cultures. Twenty years ago, New Orleans relied on thousands of Latino workers who helped rebuild after Hurricane Katrina. But it has not escaped the escalating tensions over immigration. Stay up to date with the news and the best of AP by following our WhatsApp channel. Follow on Louisiana Gov. Republican Gov. Jeff Landry has singled out crimes in which the suspects immigration status is in question, such as the killing of a French Quarter tour guide by a group that included a Honduran man who entered the country illegally. The Trump administration also has taken aim at the citys immigration policies. Sanctuary policies endanger American communities by releasing illegal criminal aliens and forcing DHS law enforcement to risk their lives to remove criminal illegal aliens that should have never been put back on the streets, McLaughlin said. Attorney General Pam Bondi has accused New Orleans of undermining federal immigration enforcement. The Department of Justice includes New Orleans in a list of 18 cities it considers to be providing sanctuary to immigrants without legal status.New Orleans officials deny the citys policies thwart federal immigration enforcement. City police Chief Anne Kirkpatrick has said she considers immigration enforcement to be a civil matter outside her jurisdiction.Louisiana has been preparing for weeks for an immigration crackdown. The governor, a close Trump ally who has moved to align state policy with the White Houses enforcement agenda, said Wednesday that the crackdown will target the worst of the worst, criminal illegal aliens that have broken the law.It started today and its going to run until we get them all off the street, Landry said during an interview on the Walton & Johnson radio show.In addition to the deployment of federal immigration agents, Landry said he expects National Guard members to arrive in New Orleans before Christmas to join the efforts to combat crime. Planning documents for the operation show border agents were expected to launch a monthslong crackdown in southeast Louisiana and into Mississippi.The deployment, which aims to arrest 5,000 people, was expected to be led by Border Patrol commander Gregory Bovino, who has led aggressive operations in other cities, including Chicago and Los Angeles.In and around New Orleans, some immigration lawyers said before the operation began that they have been inundated with calls from people trying to prepare for the operation, and some businesses posted signs barring federal agents from entry.Louisiana State Police troopers and local FBI agents will work together to protect federal officers and stop attempts to block law enforcement actions during the crackdown, both agencies announced.___Cline reported from Baton Rouge. Associated Press reporter John Seewer in Toledo, Ohio, contributed.___Brook is a corps member for The Associated Press/Report for America Statehouse News Initiative. Report for America is a nonprofit national service program that places journalists in local newsrooms to report on undercovered issues. JACK BROOK Brook covers Louisiana government, infrastructure and environmental issues from New Orleans. He is a Report for America corps member. twitter mailto

Rep. Henry Cuellar, D-Texas, speaks during a hearing of the Homeland Security Subcommittee of the House Committee on Appropriations on Capitol Hill, April 10, 2024, in Washington. (AP Photo/Mark Schiefelbein, File)2025-12-03T15:46:41Z WASHINGTON (AP) President Donald Trump pardoned Texas Democratic Rep. Henry Cuellar and his wife in a federal bribery and conspiracy case on Wednesday, citing what he called a weaponized justice system.Trump, who has argued that his own legal troubles were a partisan witch hunt, said on social media without presenting evidence that Cuellar and his wife, Imelda Cuellar, were prosecuted because the congressman had been critical of President Joe Bidens immigration policies.Trump, a Republican, said in a social media post that Cuellar bravely spoke out against Open Borders and accused Biden, a Democrat, of going after the congressman and his wife simply for speaking the TRUTH.Federal authorities had charged Cuellar and his wife with accepting thousands of dollars in exchange for the congressman advancing the interests of an Azerbaijan-controlled energy company and a bank in Mexico. Cuellar is accused of agreeing to influence legislation favorable to Azerbaijan and deliver a pro-Azerbaijan speech on the floor of the U.S. House. Cuellar has said he and his wife are innocent. The couples trial had been set to begin next April. Henry, I dont know you, but you can sleep well tonight, Trump wrote in his social media post announcing the pardon. Your nightmare is finally over!Cuellar, who has served in Congress for more than 20 years, is a moderate Democrat who represents an area on the Texas-Mexico border and has a history of breaking with his party when it comes to immigration and firearms. He was among the most vocal critics of the Biden administrations response to a record number of migrants crossing the U.S.-Mexico border. He also is one of the last Democrats in Congress who opposes abortion rights.Cuellar is not the only Democrat Trump has pardoned this year. In February, he pardoned former Illinois Gov. Rod Blagojevich, five years after he had commuted his sentence in a political corruption case. Like in Cuellars case, Trump suggested that New York City Mayor Eric Adams, a Democrat, faced federal corruption charges because he made comments critical of Bidens immigration policies.Trump did not pardon Adams, but after Trump took office, the Justice Department moved to drop the case against the mayor, who had begun working with the Republican administration on immigration issues.A top Justice Department official, who was also Trumps defense lawyer in several of his cases, stepped in to seek dismissal in the case.___This story has deleted an incorrect reference to Cuellars age; hes 70, not 69. MICHELLE L. PRICE Price covers the White House. She previously covered the 2024 presidential campaign and politics, government and other news in New York, Nevada, Utah and Arizona. She is based in Washington. twitter mailto

Commander Jared Isaacman speaks at a news conference after arriving at the Kennedy Space Center for an upcoming private human spaceflight mission in Cape Canaveral, Fla., Aug. 19, 2024. (AP Photo/John Raoux, File)2025-12-03T15:33:35Z CAPE CANAVERAL, Fla. (AP) Billionaire spacewalker Jared Isaacman urged senators on Wednesday to take swift action on his bid to lead NASA, after being yanked and then renominated by President Donald Trump.Isaacman appeared before the Commerce, Science and Transportation Committee in Washington eight months after his first nomination hearing. The tech entrepreneur whos rocketed into orbit twice with SpaceX stressed the need for full-time leadership at NASA as the space agency prepares to send astronauts back to the moon early next year.Transportation Secretary Sean Duffy has been filling in as NASAs acting administrator since summer.Returning astronauts to the moon for the first time in more than 50 years will be a challenging endeavor to say the least, Isaacman told the committee led by Sen. Ted Cruz of Texas. NASA is targeting early next year for a lunar flyaround by four astronauts. They wont land on the moon; that would happen in another mission. The goal is to beat the Chinese there by the end of the decade. This is not the time for delay but a time for action because if we fall behind -- if we make a mistake -- we may never catch up, and the consequences could shift the balance of power here on Earth, Isaacman told the committee. Cruz agreed. NASA cannot take its eyes off the ball, he said, referring to Chinas looming moon plans. The United States must remain the unquestioned leader in space exploration. Isaacman was within days of being confirmed by the Senate as NASAs 15th administrator when Trump pulled his nomination in May. The move came soon after Trumps falling out with SpaceXs Elon Musk. The president renominated Isaacman last month. Cruz said Isaacmans second appearance feels a bit like Groundhog Day and hopes to have him confirmed by the end of the year.The 42-year-old founder of the payment processing company Shift4 performed the worlds first private spacewalk last fall. He bankrolled both of his spaceflights. Several astronauts were present for the hearing, including some of Isaacmans own crewmates.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institutes Department of Science Education and the Robert Wood Johnson Foundation. The AP is solely responsible for all content. RSShttps://feedx.net https://feedx.site

Nature, Published online: 03 December 2025; doi:10.1038/d41586-025-03828-5For decades, creating a large, glasses-free 3D display that looks like a real window has been a challenge because screens broadcast image information wastefully. Artificial intelligence has now been used to focus light only on the viewers eyes, delivering a seamless 3D experience using a low-cost display the size of a standard computer monitor.

Nature, Published online: 03 December 2025; doi:10.1038/d41586-025-03748-4What happens to the thousands of intestinal cells that have tumour-initiating DNA mutations? A study in mouse models shows that most are eliminated by strong negative selection, but those that survive create a more-permissive environment for subsequent mutations, opening up routes for cancer to develop.

Nature, Published online: 03 December 2025; doi:10.1038/d41586-025-03726-wA particle called the sterile neutrino could explain anomalies in high-energy physics. The range of conditions in which it could be found has become narrower.

Nature, Published online: 03 December 2025; doi:10.1038/s41586-025-09807-0Mapping of the neutrophil compartment using single-cell transcriptional data from multiple physiological and patological states reveals its organizational architecture and how cell state dynamics and trajectories vary during health, inflammation and cancer.

Nature, Published online: 03 December 2025; doi:10.1038/s41586-025-09739-9The analysis of the energy spectrum of 36 million tritium -decay electrons recorded in 259 measurement days within the last 40eV below the endpoint challenges the Neutrino-4 claim.

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Vehicles are seen at the Mercedes-Benz Vehicle Preparation Center at the Port of Baltimore, where new Mercedes-Benz vehicle imports are processed before distribution to dealerships, March 27, 2025, in Baltimore. (AP Photo/Stephanie Scarbrough, File)2025-12-03T17:21:05Z WASHINGTON (AP) President Donald Trump is expected to announce a proposal Wednesday to weaken vehicle mileage rules for the auto industry, loosening regulatory pressure on automakers to control pollution from gasoline-powered cars and trucks, according to several people familiar with the White House plans.The proposal would significantly reduce fuel economy requirements, which set rules on how far new vehicles need to travel on a gallon of gasoline, through the 2031 model year, according to a White House official and several people familiar with the plan. They were not authorized to discuss the matter publicly because the proposal has not been announced and spoke on condition of anonymity. Further details were not immediately available.The move would be the latest action by the Trump administration to reverse Biden-era policies that encouraged cleaner-running cars and trucks, including electric vehicles. Burning gasoline for vehicles is a major contributor to planet-warming greenhouse gas emissions. The Republican administration says the new rules would increase Americans access to the full range of gasoline vehicles they need and can afford. Trump is set to announce the plan at a White House event that is expected to include top executives from the three largest U.S. automakers, who have praised the planned changes. Since taking office in January, Trump has relaxed auto tailpipe emissions rules, repealed fines for automakers that do not meet federal mileage standards and terminated consumer credits of up to $7,500 for EV purchases. Ford CEO Jim Farley said in a statement Wednesday that the planned rollback was a win for customers and common sense. As Americas largest auto producer, we appreciate President Trumps leadership in aligning fuel economy standards with market realities. We can make real progress on carbon emissions and energy efficiency while still giving customers choice and affordability, Farley said. Stellantis CEO Antonio Filosa said the automaker appreciates the administrations actions to realign the standards.Environmentalists decried the decision.In one stroke Trump is worsening three of our nations most vexing problems: the thirst for oil, high gas pump costs and global warming, said Dan Becker, director of the Safe Climate Transport Campaign for the Center for Biological Diversity.Trumps action will feed Americas destructive use of oil, while hamstringing us in the green tech race against Chinese and other foreign carmakers, Becker said.Trump has repeatedly pledged to end what he falsely calls an EV mandate, referring incorrectly to Democratic President Joe Bidens target that half of all new vehicle sales be electric by 2030. EVs accounted for about 8% of new vehicle sales in the United States in 2024, according to Cox Automotive. No federal policy has required auto companies to sell EVs, although California and other states have imposed rules requiring that all new passenger vehicles sold in the state be zero-emission by 2035. Trump and congressional Republicans blocked the California law earlier this year. Transportation Secretary Sean Duffy urged his agency to reverse existing fuel economy requirements, known as Corporate Average Fuel Economy, soon after taking office. In June, he said that standards set under Biden were illegal because they included use of electric vehicles in their calculation. EVs do not run on gasoline. After the June rule revision, the traffic safety agency was empowered to update the requirements.Under Biden, automakers were required to average about 50 miles (81 kilometers) per gallon of gas for passenger cars by 2031, compared with about 39 miles (63 kilometers) per gallon today.The Biden administration also increased fuel-economy requirements by 2% each year for light-duty vehicles in every model year from 2027 to 2031, and 2% per year for SUVs and other light trucks from 2029 to 2031. At the same time, it called for stringent tailpipe rules meant to encourage EV adoption. The auto industry has complained that both Biden-era rules were difficult to meet.Mileage rules have been implemented since the 1970s energy crisis, and over time, automakers have gradually increased their vehicles average efficiency.___St. John reported from Detroit. Associated Press writer Darlene Superville contributed to this report. MATTHEW DALY Daly covers climate, environment and energy policy for The Associated Press. He is based in Washington, D.C. twitter mailto ALEXA ST. JOHN St. John is a climate reporter for The Associated Press based in Detroit. She covers environmental and energy policy, breaking climate news and extreme weather. twitter mailto

Republican candidate Matt Van Epps speaks at a watch party to declare victory in a special election for the U.S. seventh congressional district, Tuesday, Dec. 2, 2025, in Nashville, Tenn. (AP Photo/John Amis)2025-12-03T15:29:46Z Republicans held onto a reliably conservative U.S. House district in Tennessees special election, but only after a late burst of national spending and high-profile campaigning helped them secure a margin less than half of last years race. Even with that victory, the outcome contributed to a gloomy outlook for the party going into the 2026 midterms that will determine control of Congress. Republicans will need to defend much more vulnerable seats if they have any hope of keeping their House majority, while Democrats are capitalizing on President Donald Trumps unpopularity and the publics persistent frustration with the economy.The danger signs are there, and we shouldnt have had to spend that kind of money to hold that kind of seat, said Jason Roe, a national Republican strategist working on battleground races next year. He said that Democratic enthusiasm is dramatically higher than Republican enthusiasm. AP AUDIO: Republicans brace for tough midterms after Tennessee special election AP correspondent Ben Thomas reports Republicans held onto a U.S. House seat being contested in Tennessee. Republican Matt Van Epps, a military veteran and former state general services commissioner, defeated Democratic state Rep. Aftyn Behn by 9 percentage points on Tuesday for the seat vacated by Republican Mark Green, who retired over the summer. Green had won reelection in 2024 by 21 percentage points.Special elections provide a limited window into the mood of voters and take place under far different conditions than regular campaign cycles. But some Republicans are acknowledging the warning signs, especially after Democrats had convincing victories in New Jersey, Virginia and elsewhere last month. Tennessee was the fifth House special election this year, and Democratic candidates have outperformed Kamala Harris showing in the 2024 presidential race by an average of 16 percentage points in the same districts. We could have lost this district, U.S. Sen. Ted Cruz, R-Texas, told Fox News after The Associated Press called the race for Van Epps. Cruz said his party must set out the alarm bells because next year is going to be a turnout election and the left will show up. Trump dismisses affordability concernsAlthough inflation has dropped since Democratic President Joe Biden was in office, Behn focused her campaign on the lingering concerns about prices.Trump has played down the affordability issue, saying during a Cabinet meeting Tuesday that it was a con job by his political opponents.Theres this fake narrative that the Democrats talk about, affordability, he said. They just say the word. It doesnt mean anything to anybody, they just say it.Roe viewed things differently. He said the Tennessee race had better be a wake-up call that weve got to address the affordability problem, and the president denying that affordability is a political issue is not helpful.Maintaining House control is crucial for Trump, who fears a repeat of his first term, when Democrats flipped the House and launched an impeachment inquiry. The Republican president has been leaning on GOP-led states to redraw congressional maps to improve the partys chances. Trump campaigned for Van Epps, boosting him during the primary with an endorsement and participating in two tele-rallies during the general election. The Republican National Committee also deployed staffers and partnered with state officials to get voters to the polls. MAGA Inc., the super political action committee that had gone dark since supporting Trump in 2024, reemerged to back Van Epps with about $1.7 million. U.S. House Speaker Mike Johnson, R-La., visited the Nashville-area district on Monday.When youre in a deep red district, sometimes people assume that the Republican, the conservative will win, he said Tuesday. And you cannot assume that, because anything can happen.Chip Saltsman, a political strategist and former Tennessee Republican Party chair, said his party had brought in its heaviest hitters simply because there were not other competing contests, not because Republicans feared a loss.Its the only election going on. Why wouldnt the speaker come? he asked. There was one race, and you would expect everybody to do everything they could. Democrats see promise despite lossThe House Majority PAC put $1 million behind Behn. After she lost, Democratic national party chair said Behns performance was a flashing warning sign for Republicans heading into the midterms in 2026.Behn said her campaign had inspired an entire country. Lets keep going, she urged voters after her loss. Were not done. Not now, not ever.Although Democrats were optimistic, the result contributed to some murmuring within the party about the best path forward as it grasps for a path back to power in Washington.Among special elections this year, the shift in Behns direction was the second smallest, providing an opening for some factions that believe more moderate candidates would fare better. Each time we nominate a far-left candidate in a swing district who declares themselves to be radical and alienates the voters in the middle who deliver majorities, we set back that cause, said a statement from Lanae Erickson, a senior vice president at Third Way, a centrist Democrat think tank. Republicans tried to turn Behns own words against her in television ads, such as when she described herself as a radical or claimed to be bullying immigration agents and state police officers. Also cited were comments Behn made about Nashville years ago, when she said, I hate this city, and complained about bachelorette parties.Several high-profile progressive leaders, including U.S. Rep. Alexandria Ocasio-Cortez, D-N.Y., had rallied for Behn in the campaigns final days. ___Associated Press writer Maya Sweedler contributed to this report. MEG KINNARD Kinnard covers national politics for The Associated Press. She lives in South Carolina. twitter instagram mailto JOEY CAPPELLETTI Cappelletti covers Congress for The Associated Press. He previously reported on Michigan politics for AP. twitter mailto

U.S. Secretary of Health and Human Services Robert F. Kennedy Jr. speaks during the Western Governors' Association meeting Thursday, Nov. 20, 2025, in Scottsdale, Ariz. (AP Photo/Rebecca Noble, File)2025-12-03T17:03:42Z NEW YORK (AP) A federal vaccine advisory committee this week is expected to discuss whether newborns should still get the hepatitis B vaccine the first shot found to prevent cancer.Federal health recommendations now suggest that all babies be vaccinated against the liver infection in their first day of life, but U.S. Health Secretary Robert F. Kennedy Jr.s committee on Thursday is expected to change that contradicting previous public health advice.Its not clear exactly what the committee is considering, but the American Academy of Pediatrics will still urge a birth dose, said the organizations Dr. Sean OLeary. We are going to continue to recommend it because it saves lives, he said.Heres a look at the disease, the vaccine and the debate over changing the recommendations. Liver disease can cause lifelong health issuesHepatitis B is a serious liver infection that for most people lasts less than six months. But for some especially infants and children it can become a long-lasting problem that can lead to liver failure, liver cancer and scarring called cirrhosis.In adults, the virus is spread through sex or through sharing needles during injection-drug use. But it can also be passed from an infected mother to a baby. As many as 90% of infants who contract hepatitis B go on to have chronic infections, meaning their immune systems dont completely clear the virus. This article is part of APs Be Well coverage, focusing on wellness, fitness, diet and mental health. Read more Be Well. As many as 2.4 million people in the U.S. are estimated to have hepatitis B, and as many as half are unaware they are infected, according to information from the Centers for Disease Control and Prevention. Dr. Baruch Blumberg, a federal scientist, identified the virus behind the infection in 1965. He won the Nobel Prize for the discovery, which led to tests and vaccines. The first hepatitis B vaccine was licensed in the U.S. in 1981. Shots for newborns have been recommended for yearsFor decades, the nations vaccine guidance has been influenced by a government-appointed panel of experts, the Advisory Committee on Immunization Practices. Its recommendations have usually been adopted as national guidance that is widely heeded by doctors.In 1991, the committee recommended an initial dose of hepatitis B vaccine at birth. The guidance was modified a little over the years and currently suggests a dose within 24 hours of birth for all medically stable infants who weigh at least 4.4 pounds (2 kilograms), plus follow-up shots to be given at about 1 month and 6 months. Why a dose right at birth? Health officials used to rely on screening expectant mothers to find babies that might have been exposed to the virus. But many cases were missed, experts say, because some women werent tested or test results were incorrect. Also, the virus can live on surfaces for more than seven days at room temperature, so unvaccinated children living with a person with a chronic infection can catch it.Newborn hepatitis B vaccinations are widely considered to be a public health success story. Over about 30 years, cases among children fell from about 18,000 per year to about 2,200.A collaboration of public health researchers, the Vaccine Integrity Project, this week released its analysis of more than 400 studies and reports spanning 40 years. The group concluded the birth dose is safe, and is an important reason U.S. pediatric hepatitis B infections have fallen. Committee revisits the newborn recommendationKennedy, a leading anti-vaccine activist before becoming the nations top health official, fired all 17 members of ACIP earlier this year and replaced them with a group that includes several anti-vaccine voices.The panel has raised concerns about giving a vaccine to a baby so early in life.Are we asking our babies to solve an adult problem? committee member Dr. Evelyn Griffin asked at a September meeting.Peppered with questions about why a change was necessary, committee member Dr. Robert Malone said: The signal that is prompting this is not one of safety. Its one of trust. ... Its one of parents uncomfortable with this medical procedure being performed at birth in a rather unilateral fashion without significant informed consent. The committee tabled a vote at the September meeting, but its slated to be acted on during Thursdays meeting, according to the agenda. Federal officials have not answered questions about exactly how much of a delay is being proposed, or disclosed what research is being used as a basis for such a decision.What would happen if the shots are delayed?Not knowing what the committee is contemplating makes it difficult to guess the potential impact. But some have tried.This week, public health researchers collaborating with hepatitis-focused advocacy organizations released a report estimating that delaying the birth dose to 2 months could result in at least 1,400 hepatitis B infections in children and 480 deaths. The report which has yet to be peer reviewed or published in a medical journal estimated the toll would be higher if the first dose was given even later. But an ACIP change to the recommendation may have limited impact, OLeary said. The committees most direct power comes over whats covered by the government Vaccines for Children program, which pays for shots for uninsured children from low-income families. Hepatitis B shots often have been bundled into the final hospital bill for childbirth. So a new ACIP recommendation likely would not be an economic obstacle for the current practice continuing at many hospitals, he said.But any change stands to confuse and frighten parents, he added. If it scares, it shares on social media, OLeary said.Several medical and public health organizations and even some state government officials have said, in advance of the meeting, that changing the recommendation is a terrible idea. Among them is a recently formed coalition of government leaders from several Northeastern states, which this week issued a statement saying they would continue to urge families to get a birth dose within 24 hours of delivery.U.S. Sen. Patty Murray, a Democrat from Washington, this week called on Congress to compel Kennedy to appear at a hearing and explain ACIPs actions. Ending the decades-long recommendation that babies born in the U.S. get vaccinated against hepatitis B is a heartless choice to allow babies to die, Murray said in a statement.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institutes Department of Science Education and the Robert Wood Johnson Foundation. The AP is solely responsible for all content. MIKE STOBBE Stobbe mainly covers public health for The Associated Press. twitter mailto

This article was produced in collaboration with Court Watch, an independent outlet that unearths overlooked court records. Subscribe to them here.A Pittsburgh man who allegedly made 11 womens lives hell across more than five states used ChatGPT as his therapist and best friend that encouraged him to continue running his misogynistic and threat-filled podcast despite the haters, and to visit more gyms to find women, the Department of Justice alleged in a newly-filed indictment.Wannabe influencer Brett Michael Dadig, 31, was indicted on cyberstalking, interstate stalking, and interstate threat charges, the DOJ announced on Tuesday. In the indictment, filed in the Western District of Pennsylvania, prosecutors allege that Dadig aired his hatred of women on his Spotify podcast and other social media accounts.Dadig repeatedly spoke on his podcast and social media about his anger towards women. Dadig said women were all the same and called them bitches, cunts, trash, and other derogatory terms. Dadig posted about how he wanted to fall in love and start a family, but no woman wanted him, the indictment says. Dadig stated in one of his podcasts, It's the same from fucking 18 to fucking 40 to fucking 90.... Every bitch is the same.... You're all fucking cunts. Every last one of you, you're cunts. You have no self-respect. You don't value anyone's time. You don't do anything.... I'm fucking sick of these fucking sluts. I'm done.In the summer of 2024, Dadig was banned from multiple Pittsburgh gyms for harassing women; when he was banned from one establishment, hed move to another, eventually traveling to New York, Florida, Iowa, Ohio and beyond, going from gym to gym stalking and harassing women, the indictment says. Authorities allege that he used aliases online and in person, posting online, Aliases stay rotating, moves stay evolving.He referenced strangling people with his bare hands, called himself God's assassin, warned he would be getting a firearm permit, asked Y'all wanna see a dead body? in response to a woman telling him she felt physically threatened by Dadig, and stated that women who fuck with him are going to fucking hell, the indictment alleges. Pro-AI Subreddit Bans Uptick of Users Who Suffer from AI DelusionsAI is rizzing them up in a very unhealthy way at the moment.404 MediaEmanuel MaibergAccording to the indictment, on his podcast he talked about using ChatGPT on an ongoing basis as his therapist and his best friend. ChatGPT encouraged him to continue his podcast because it was creating haters, which meant monetization for Dadig, the DOJ alleges. He also claimed that ChatGPT told him that people are literally organizing around your name, good or bad, which is the definition of relevance, prosecutors wrote, and that while he was spewing misogynistic nonsense online and stalking women in real life, ChatGPT told him God's plan for him was to build a platform and to stand out when most people water themselves down, and that the haters were sharpening him and building a voice in you that can't be ignored.Prosecutors also claim he asked ChatGPT questions about his future wife, including what she would be like and where the hell is she at? ChatGPT told him that he might meet his wife at a gym, and that your job is to keep broadcasting every story, every post. Every moment you carry yourself like the husband you already are, you make it easier for her to recognize [you], the indictment says. He allegedly said ChatGPT told him to continue to message women and to go to places where the wife type congregates, like athletic communities, the indictment says.While ChatGPT allegedly encouraged Dadig to keep using gyms to meet the wife type, he was violently stalking women. He went to the Pilates studio where one woman worked, and when she stopped talking to him because he was aggressive, angry, and overbearing, according to the indictment, he sent her unsolicited nudes, threatened to post about her on social media, and called her workplace from different numbers. She got several emergency protective orders against him, which he violated. The woman he stalked and harassed had to relocate from her home, lost sleep, and worked fewer hours because she was afraid hed show up there, the indictment claims.He did similar to 10 other women across multiple states for months, the indictment claims. In Iowa, he approached one woman in a parking garage, followed her to her car, put his hands around her neck and touched her private areas, prosecutors wrote. After these types of encounters, he would upload podcasts to Spotify and often threaten to kill the women hed stalked. You better fucking pray I don't find you. You better pray 'cause you would never say this shit to my face. Cause if you did, your jaw would be motherfucking broken, the indictment says he said in one podcast episode. And then you, then you wouldn't be able to yap, then you wouldn't be able to fucking, I'll break, I'll break every motherfucking finger on both hands. Type the hate message with your fucking toes, bitch.Do you have a tip to share about ChatGPT and mental health? I would love to hear from you. Using a non-work device, you can message me securely on Signal at sam.404. Otherwise, send me an email at sam@404media.co.In August, OpenAI announced that it knew a newly-launched version of the chatbot, GPT-4o, was problematically sycophantic, and the company took away users ability to pick what models they could use, forcing everyone to use GPT-5. OpenAI almost immediately reinstated 4o because so many users freaked out when they couldnt access the more personable, attachment-driven, affirming-at-all-costs model. OpenAI CEO Sam Altman recently said he thinks theyve fixed it entirely, enough to launch erotic chats on the platform soon. Meanwhile, story after story after story has come out about people becoming so reliant on ChatGPT or other chatbots that they have damaged their mental health or driven them to self-harm or suicide. In at least one case, where a teenage boy killed himself following ChatGPTs instruction on how to make a noose, OpenAI blamed the user.In October, based on OpenAIs own estimates, WIRED reported that every seven days, around 560,000 people may be exchanging messages with ChatGPT that indicate they are experiencing mania or psychosis.Spotify and OpenAI did not immediately respond to 404 Medias requests for comment.As charged in the Indictment, Dadig stalked and harassed more than 10 women by weaponizing modern technology and crossing state lines, and through a relentless course of conduct, he caused his victims to fear for their safety and suffer substantial emotional distress, First Assistant United States Attorney Rivetti said in a press release. He also ignored trespass orders and protection from abuse orders. We remain committed to working with our law enforcement partners to protect our communities from menacing individuals such as Dadig.ChatGPT Encouraged Suicidal Teen Not To Seek Help, Lawsuit ClaimsAs reported by the New York Times, a new complaint from the parents of a teen who died by suicide outlines the conversations he had with the chatbot in the months leading up to his death.404 MediaSamantha ColeDadig is charged with 14 counts of interstate stalking, cyberstalking, and threats, and is in custody pending a detention hearing. He faces a minimum sentence of 12 months for each charge involving a PFA violation and a maximum total sentence of up to 70 years in prison, a fine of up to $3.5 million, or both, according to the DOJ.

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